DRSC/TRiP Functional Genomics Resources

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Protein Alignment erm and egr2b

DIOPT Version :9

Sequence 1:NP_001259891.2 Gene:erm / 326152 FlyBaseID:FBgn0031375 Length:698 Species:Drosophila melanogaster
Sequence 2:NP_571072.2 Gene:egr2b / 30190 ZFINID:ZDB-GENE-980526-283 Length:412 Species:Danio rerio


Alignment Length:387 Identity:93/387 - (24%)
Similarity:133/387 - (34%) Gaps:127/387 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   136 ATSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLS 200
            |.||..:.|:....|.|.......:.||||..:.....:...:|    ..|...|.|.||::..|
Zfish    72 AYSSSFAQPAGPRNQTFTYMGKFSIDSQYPGNWNPEGVINIVSA----GILGMTQPSSASSSPAS 132

  Fly   201 SFTASLNASLHHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQSSGLQANL 265
            |.:.|     |.|.:|.             ..:||:||  :::|.....|      ..||.    
Zfish   133 SVSPS-----HFSSTLS-------------CTMAQNQA--DMEHIYSPPP------PYSGC---- 167

  Fly   266 KRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGGKP--------------- 315
                     |||...|::..:::|...|..|.   |.....|.:.||..|               
Zfish   168 ---------GEVYQDPSAFLSTSTCPISYPPP---SYSSPKPNADSGLFPIIPDYAGFFQPPCQR 220

  Fly   316 --------KTFSC-LECGKV------FNAHYNLTRHMPVHTG----------------------- 342
                    |.||| |:..|:      .|...|.|...||..|                       
Zfish   221 DMQSMPDRKPFSCPLDSFKLPPPLTPLNTIRNFTLGGPVPDGPRLPTAYTPQNLPLRPILRPRKY 285

  Fly   343 ----------ARPFVCKV--CGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRI 395
                      .||:.|..  |.:.|.::..|.||..|||..||.:|:.|.:.|:||..|.||.|.
Zfish   286 PNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRT 350

  Fly   396 HAGYKPFVCEYCGKGFHQKGNYKNHKLTH----------------SGEKAYKCNICNKAFHQ 441
            |.|.|||.|::||:.|.:....|.|...|                |.|:....:||:.:.:|
Zfish   351 HTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERKSSSSSTGVSSSERGVATSICSSSSNQ 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ermNP_001259891.2 COG5048 <295..461 CDD:227381 57/228 (25%)
C2H2 Zn finger 320..340 CDD:275368 7/26 (27%)
zf-H2C2_2 332..357 CDD:290200 10/59 (17%)
zf-C2H2 346..368 CDD:278523 6/23 (26%)
C2H2 Zn finger 348..368 CDD:275368 6/21 (29%)
zf-H2C2_2 363..385 CDD:290200 10/21 (48%)
C2H2 Zn finger 376..396 CDD:275368 9/19 (47%)
zf-H2C2_2 389..413 CDD:290200 13/23 (57%)
C2H2 Zn finger 404..424 CDD:275368 6/19 (32%)
zf-H2C2_2 416..441 CDD:290200 7/40 (18%)
C2H2 Zn finger 432..452 CDD:275368 3/10 (30%)
C2H2 Zn finger 460..478 CDD:275368
egr2bNP_571072.2 DUF3446 92..164 CDD:288757 22/101 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 269..299 1/29 (3%)
COG5048 295..>357 CDD:227381 25/61 (41%)
zf-C2H2 299..323 CDD:278523 6/23 (26%)
C2H2 Zn finger 301..323 CDD:275368 6/21 (29%)
zf-H2C2_2 315..340 CDD:290200 11/24 (46%)
COG5048 327..>411 CDD:227381 27/83 (33%)
C2H2 Zn finger 331..351 CDD:275368 9/19 (47%)
zf-H2C2_2 343..368 CDD:290200 13/24 (54%)
C2H2 Zn finger 359..379 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 371..412 7/40 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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