DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment erm and ztf-6

DIOPT Version :9

Sequence 1:	NP_001259891.2	Gene:	erm / 326152	FlyBaseID:	FBgn0031375	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	NP_492877.1	Gene:	ztf-6 / 173014	WormBaseID:	WBGene00012317	Length:	480	Species:	Caenorhabditis elegans

Alignment Length:	359	Identity:	86/359 - (23%)
Similarity:	132/359 - (36%)	Gaps:	63/359 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 HRPSQVPPPQPAPVSFATNDDDEDEDPEIDADSERSCSPIEVISL--DQSPSTV----NYDSAFK 126
            ||.|:.||.:....:...:||:|.|...|::.|.||.|.....|.  |::..|:    :......
Worm   105 HRSSEEPPRRKPSAAGGDHDDEELECSSIESRSIRSVSSSVHTSAEDDETNQTMMVPTDVADVIN 169

  Fly   127 KYVPG----PCSGATSSVASP------------------PSTAAVQQFVSSRHQELLSQYPLLYY 169
            ..|.|    ..|..|||..||                  .||:..:..:|.:.:..|....||
Worm   170 AIVAGTNGSSNSNTTSSSKSPQEEEEEHDLVMKSILSTTTSTSNTKLELSEKLENPLQDTALL-- 232

  Fly   170 APNQLMCAAAAAQYAALT----AQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAV 230
              :|.:.|:...|...:|    ..::.....|.|:||...|.|:.....::       |.|.::.
Worm   233 --DQFLQASLLGQTPTVTPASEENEEDKEQNAVLTSFLQILFANQQAGNAI-------LDAGSSE 288

  Fly   231 AAVAQSQAVPNLQHTLEKSPVAQRTAQSSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRS 295
            ...:.|.:.|        ||.|..||....| |..:...:....|.|.....|:|.....||.|.
Worm   289 NDGSTSSSQP--------SPPADPTASLDSL-AMFESLLAESMNGNVLDANTSSADQKAAARKRK 344

  Fly   296 PSPQGSIEDSSPGSASGGKPKTFSCL--ECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQA 358
            .:|.     ..|.|.:|.   .:.|.  .|.|||....::.||...|.|.| |.|..|...:.|.
Worm   345 STPM-----KVPKSENGA---GYICPMDGCNKVFKEKGSVHRHFVTHIGMR-FNCDKCKASYTQK 400

  Fly   359 STLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTH 392
            ..|..|:.||.:...::|:.||..:...:.|..|
Worm   401 HALMLHQKIHANPDAYQCRGCGTNYTTQNGLRLH 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	27/100 (27%)
		C2H2 Zn finger	320..340	CDD:275368	7/21 (33%)
		zf-H2C2_2	332..357	CDD:290200	8/24 (33%)
		zf-C2H2	346..368	CDD:278523	6/21 (29%)
		C2H2 Zn finger	348..368	CDD:275368	5/19 (26%)
		zf-H2C2_2	363..385	CDD:290200	6/21 (29%)
		C2H2 Zn finger	376..396	CDD:275368	5/17 (29%)
		zf-H2C2_2	389..413	CDD:290200	2/4 (50%)
		C2H2 Zn finger	404..424	CDD:275368
		zf-H2C2_2	416..441	CDD:290200
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..478	CDD:275368
ztf-6	NP_492877.1	zf-C2H2_8	361..434	CDD:292531	22/73 (30%)
		C2H2 Zn finger	361..383	CDD:275368	7/21 (33%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		C2H2 Zn finger	418..435	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I4043
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050