DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment erm and Osr2

DIOPT Version :9

Sequence 1:NP_001259891.2 Gene:erm / 326152 FlyBaseID:FBgn0031375 Length:698 Species:Drosophila melanogaster
Sequence 2:NP_001355594.1 Gene:Osr2 / 107587 MGIID:1930813 Length:312 Species:Mus musculus


Alignment Length:346 Identity:99/346 - (28%)
Similarity:126/346 - (36%) Gaps:90/346 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   170 APNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRN---LGHPLAAAAAVA 231
            ||..|..:.....|:.|.|.....|:..||...     ..|...|::..|   ||:|..      
Mouse     8 APIPLHPSLQLTNYSFLQAVNTFPAAVDHLQGL-----YGLSAVQTMHMNHWTLGYPSV------ 61

  Fly   232 AVAQSQAVPNLQHTLEKSPVAQRTAQSSGLQANLKRKRSP-------QDQG---EVTP------P 280
                        |.:.:|.:.:..|....:.|.......|       ..||   .|.|      |
Mouse    62 ------------HEITRSTITEMAAAQGLVDARFPFPSLPFATHLFHPKQGAIAHVLPALHKDRP 114

  Fly   281 PASTATSATGARSRSPSPQGSIEDSSPGSAS----------------GGKP----KTFSCLECGK 325
            ....|..|..|....|...|.:...|||..|                |..|    |.|.|..||:
Mouse   115 RFDFANLAVAATQEDPPKMGDLSKLSPGLGSPISGLSKLNPDRKPSRGRLPSKTKKEFICKFCGR 179

  Fly   326 VFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLN 390
            .|...|||..|...||..||:.|.:|.|.||:...|..|:.||:.|||.|||.|||.|.:|.||.
Mouse   180 HFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLA 244

  Fly   391 THSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDK 455
            .|..:|....|..|..||:.|:|:.|.|.|.|||:                            |.
Mouse   245 VHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHT----------------------------DI 281

  Fly   456 KPYTCRVCAKGFCRNFDLKKH 476
            |||:|..|.|.|.||.||::|
Mouse   282 KPYSCEQCGKVFRRNCDLRRH 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ermNP_001259891.2 COG5048 <295..461 CDD:227381 62/185 (34%)
C2H2 Zn finger 320..340 CDD:275368 8/19 (42%)
zf-H2C2_2 332..357 CDD:290200 11/24 (46%)
zf-C2H2 346..368 CDD:278523 7/21 (33%)
C2H2 Zn finger 348..368 CDD:275368 7/19 (37%)
zf-H2C2_2 363..385 CDD:290200 13/21 (62%)
C2H2 Zn finger 376..396 CDD:275368 10/19 (53%)
zf-H2C2_2 389..413 CDD:290200 8/23 (35%)
C2H2 Zn finger 404..424 CDD:275368 9/19 (47%)
zf-H2C2_2 416..441 CDD:290200 6/24 (25%)
C2H2 Zn finger 432..452 CDD:275368 0/19 (0%)
C2H2 Zn finger 460..478 CDD:275368 9/17 (53%)
Osr2NP_001355594.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 146..165 1/18 (6%)
C2H2 Zn finger 174..194 CDD:275368 8/19 (42%)
zf-H2C2_2 186..211 CDD:338759 11/24 (46%)
C2H2 Zn finger 202..222 CDD:275368 7/19 (37%)
zf-H2C2_2 214..237 CDD:338759 13/22 (59%)
C2H2 Zn finger 230..250 CDD:275368 10/19 (53%)
COG5048 251..>312 CDD:227381 25/80 (31%)
C2H2 Zn finger 258..278 CDD:275368 9/19 (47%)
C2H2 Zn finger 286..306 CDD:275368 9/17 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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