Protein Alignment erm and nacc2

DIOPT Version :10

• Sequence 1: NP_001259891.2
• Gene: erm / 326152
• FlyBaseID: FBgn0031375
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001096544.1
• Gene: nacc2 / 100125188
• XenbaseID: XB-GENE-986407
• Length: 577
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 114/563 - (20%)
• Similarity: 174/563 - (30%)
• Gaps: 165/563 - (29%)

  Fly   134 SGATSSVASPPST---AAVQQFVSSRHQELLSQYPLLYYAPNQL--MCAAAAAQYAALTAQQQSL 193
            ||.:.|....|:|   |..||.:|..:...|:.     .|..||  |..|...|...:..:...|
 Frog    60 SGNSKSAFELPATVPPACFQQILSFCYTGKLTM-----AASEQLVVMYTAGFLQIQHIVERGTDL 119

  Fly   194 ---ASAAHLSSFTASLNASLHHSQS-------------LRRNLGHPLAAAAAVAAV-AQSQAVPN 241
               .|:.|..|.|..:..:....||             :..::..||.......:: .|..||||
 Frog   120 MFKVSSPHCDSQTTMIEDASSEPQSPCNQTQPPSGPYVMSPSMPIPLLTRVKNESLELQPIAVPN 184

  Fly   242 LQHTLEKSPVAQRTAQSSGLQANLKR-------------------KRSPQDQGEVTPPPAS---T 284
            :.   .|.||..|....|...||.::                   ::....|||.|.|.||   |
 Frog   185 MP---VKRPVENRDNGGSISTANHQKLSRLSYYGMSSLAALFPNVQQVQYSQGERTSPGASSIPT 246

  Fly   285 ATSATGARSRSPSPQ------------GSIEDSSPGSASG-GKPKTFSCLECGKVFNAHYNLTRH 336
            ..|.|...:......            |.|...|..|.|| .|......||     |....|.|.
 Frog   247 TDSPTSYHNEEDEEDDEAYDTMVEEHYGQIYMKSTSSYSGQDKTDQIPALE-----NRSCVLIRR 306

  Fly   337 MPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQT---CGKAFNRSSTLNTHSRIHAG 398
            ..|...| ..:.::   |:|     |..|:....:...|.:.   .|....|...:|.|  :.||
 Frog   307 DLVALPA-SLISQI---GYR-----CHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCH--LCAG 360

  Fly   399 YKPFVCEYCGKGFHQKGNYKNHK------LTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKP 457
            .|                   ||      |....::....|.|......       ..:...:||
 Frog   361 VK-------------------HKVLLRRLLATFFDRNTLANSCGTGIRS-------STSDPSRKP 399

  Fly   458 YTCRV--CAKGFCRNFDLKKHMRKLHEIGGDL--------------------DDLDM-------- 492
            ...||  ..|.:|:||.......:::.|..|:                    |.::|
 Frog   400 LDSRVLNAVKLYCQNFAPNFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPDGVEMYRSVMGAT 464

  Fly   493 PPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSAVSQY 557
            .||.....:: :..| |..:||.........|:..:|...|.....|::|  |||.:.:|..::.
 Frog   465 APTIPLEPDF-QPSP-AQAFGQRIYAERRSDSAAILSLRTNAANIDLTNG--SNPPFEQSEEAEG 525

  Fly   558 PPGGFHHQLG------------VAPPHDYPSGSAFLQLQPQQP 588
            ..|....::|            .|||.:..:||.   .:|:.|
 Frog   526 ATGSVIQEVGGTDPLASDAQGSPAPPFEEEAGST---SRPETP 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	33/187 (18%)
		C2H2 Zn finger	320..340	CDD:275368	5/19 (26%)
		C2H2 Zn finger	348..368	CDD:275368	4/19 (21%)
		zf-H2C2_2	363..385	CDD:463886	3/24 (13%)
		C2H2 Zn finger	376..396	CDD:275368	4/22 (18%)
		C2H2 Zn finger	404..424	CDD:275368	3/25 (12%)
		C2H2 Zn finger	432..452	CDD:275368	2/19 (11%)
		C2H2 Zn finger	460..478	CDD:275368	6/19 (32%)
nacc2	NP_001096544.1	BTB_POZ_BTBD14A_NAC2	1..131	CDD:349598	19/75 (25%)
		BEN	364..441	CDD:214981	14/83 (17%)