Protein Alignment Pgant5 and GALNT4

DIOPT Version :9

• Sequence 1: NP_001036338.1
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_003765.2
• Gene: GALNT4 / 8693
• HGNCID: 4126
• Length: 578
• Species: Homo sapiens
• Alignment Length: 517
• Identity: 235/517 - (45%)
• Similarity: 314/517 - (60%)
• Gaps: 38/517 - (7%)

  Fly   130 GEMGKPVKIPADMKDL--MKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASK-LPTTSI 191
            ||.||..|:..:..:|  .:|..:....|:..||.|||:|.:.|.|...|:.:.:..: |||||:
Human    75 GEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSV 139

  Fly   192 VIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEK 256
            :|.|:||||:|||||:.||:..||..||||||||||.|:|.:|..|||.|::.|. :..::||.|
Human   140 IIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLD-RVRLIRTNK 203

  Fly   257 RSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFE-YI 320
            |.||:||||:||...:|:|:||||.||||..|||||||.||.::...||||:||.|...||| |:
Human   204 REGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYM 268

  Fly   321 TASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMD 385
            ...:...|||:|:|.|:|:.||.:|..||.: |..|:|:||||||||::.|.||..:|:||.||:
Human   269 QIGEPMIGGFDWRLTFQWHSVPKQERDRRIS-RIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGME 332

  Fly   386 IWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKE 450
            :|||||||:|||||.|||.|||.|||.|||||.|..||..|.     ...|.||..|||:|::||
Human   333 VWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPYARPN-----FLQNTARAAEVWMDEYKE 392

  Fly   451 FYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDY-YYLGEIRN-AETETC 513
            .:|:..|.|||.:.||:|:||.||:||:||||.|||:||:|...:|.|. .:.|.||: ..:..|
Human   393 HFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRSRGISSEC 457

  Fly   514 LDTMGRKYNE--------KVGISYCHGLGGNQVFAYTKRQQIMSD---DLCLDASSSNGPVNMVR 567
            ||     ||.        .:.:..|||.||||.|.||..::|..:   :||.:.......|.|..
Human   458 LD-----YNSPDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQKNYVGMQN 517

  Fly   568 CHNMG----GNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTP--LLRPC-SYGKGQQWLME 622
            |...|    .|..|.: .|:..|.|.::|.||. |.|.....|  .:|.| :..|.|.|..|
Human   518 CPKDGFPVPANIIWHF-KEDGTIFHPHSGLCLS-AYRTPEGRPDVQMRTCDALDKNQIWSFE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	168/300 (56%)
		Ricin_B_lectin	503..619	CDD:395527	40/134 (30%)
GALNT4	NP_003765.2	Catalytic subdomain A	134..243		67/109 (61%)
		pp-GalNAc-T	138..432	CDD:133004	168/300 (56%)
		Catalytic subdomain B	303..365		43/61 (70%)
		Ricin_B_lectin	446..574	CDD:395527	40/134 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750