DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt9

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_001338018.1	Gene:	galnt9 / 797549	ZFINID:	ZDB-GENE-060526-21	Length:	604	Species:	Danio rerio

Alignment Length:	659	Identity:	219/659 - (33%)
Similarity:	319/659 - (48%)	Gaps:	115/659 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLTSLVWVIFDFVLIARYSDC-----------IGK------DGWRCKRSGEYDVE--LPNAERLV 68
            |||..:.|....:|.:.|  |           ||:      .|...|.:...|.:  |...|||.
Zfish    10 LLTVNILVFVGIILFSVY--CRIQDRSEELVQIGRLSDQRLRGRNAKVTNSMDRQSILKRLERLE 72

  Fly    69 DDNQLVDDNEINTEKSLDGESGGALIMG-----QGFASGGISMTYPSVVLKKWFLAPSVQEAKGK 128
            |    |..|::|         |.|..||     .|...||.:.|          |....:|.:|
Zfish    73 D----VVYNQLN---------GLAKPMGLVEGPGGLGQGGAAAT----------LGEDSRETEG- 113

  Fly   129 PGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVI 193
                                :|:|..:|...||.|||:|::.|.|.:.|::..|:..||..|:|.
Zfish   114 --------------------RFEEYGYNAQLSDRISLDRNIPDYRPKKCKQLTYSDDLPQISVVF 158

  Fly   194 VFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAK-LPVKTFVLRTEKR 257
            :|.|||.:.:||:|.|::|.:|..||||||||||.|:...|...|:.||.| .|....::|..||
Zfish   159 IFVNEALSVILRSVHSMVNHTPAHLLKEIILVDDNSDSVELKFNLDHYVNKRYPGLVKIVRNSKR 223

  Fly   258 SGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFE---Y 319
            .||||||:.|....:..|:.|.|||.|....|.||:|.|:.::...::.|.||.|...|||   |
Zfish   224 EGLIRARIHGWNAATAPVVGFFDAHVEFNTAWAEPILTRVKEDHTRIILPAIDNIKYNTFEVQQY 288

  Fly   320 ITASDSTWGGFNWKLNFRW--YRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDE 382
            ..|:.    |:||.|   |  |.:|.::...| .|.|||:|||.|.|..|.:|::||.|||..|.
Zfish   289 ANAAH----GYNWGL---WCMYIIPPQDWLDR-GDETAPIRTPAMIGCSFVVDREYFGEIGLLDP 345

  Fly   383 GMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDD 447
            ||:::||||:|:..|||.|||.:|:.||:||.|:.|...||.  .........|..|..|||:|:
Zfish   346 GMEVYGGENIELGMRVWQCGGSMEVLPCARVAHIERTKKPYN--NDIDYYAKRNALRAAEVWMDE 408

  Fly   448 WKEFYYSFY------PGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIR 506
            :|...|..:      ||   ...||||:|.|||.::.|||||||||:||||..:..:....||:|
Zfish   409 FKSHVYMAWNIPMNNPG---VDFGDVSERVALRKKMNCKSFRWYLEHVYPEMRIYNNTITYGEVR 470

  Fly   507 NAETE-TCLDTMGRKYNEKVGISYCHGLGGNQVFAYTKR----------QQIMSDDLCLDASSSN 560
            |::.. .||| .|.:.:|:..:..|||: .:|:..||..          ...:.|..||......
Zfish   471 NSKASGYCLD-QGSEEDERAILYPCHGM-SSQLARYTTEGLLQLGPLGSTTFLPDTKCLVDDGRG 533

  Fly   561 GPVNMVRCHNMGGNQEWVYDAEEKW-IRHTNTGQCLQRATRDDANTPL---LRPCSYGKGQQWLM 621
            ...::.:|.::..:.:.::|..:.. |...:||:||:.....|||..|   ::.||   ||:|::
Zfish   534 RTPSLKKCDSVTRSSQRLWDFTQNGPIISRDTGRCLEVEMSKDANFGLRLVVQRCS---GQKWMI 595

  Fly   622 ESKFKWQAH 630
            .:..|...|
Zfish   596 RNWIKHPRH 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	133/311 (43%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	33/130 (25%)
galnt9	XP_001338018.1	pp-GalNAc-T	155..454	CDD:133004	133/311 (43%)
		Ricin_B_lectin	465..593	CDD:279046	33/132 (25%)
		RICIN	467..595	CDD:238092	34/132 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740