Protein Alignment Pgant5 and GALNT12

DIOPT Version :9

• Sequence 1: NP_001036338.1
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_078918.3
• Gene: GALNT12 / 79695
• HGNCID: 19877
• Length: 581
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 226/512 - (44%)
• Similarity: 315/512 - (61%)
• Gaps: 25/512 - (4%)

  Fly   130 GEMGKPVKIPADMKD--LMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHY-ASKLPTTSI 191
            |..|:.|::....::  |.:|..:.:|.|:..||.|||:|.|.:..:..|:.|.| ...||.||:
Human    76 GARGEAVRLQLQGEELRLQEESVRLHQINIYLSDRISLHRRLPERWNPLCKEKKYDYDNLPRTSV 140

  Fly   192 VIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEK 256
            :|.|:||||:||||||:||:..||..||:|:|||||.|:|:.|.::|...::.|| |..::|..|
Human   141 IIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLANELSGLP-KVRLIRANK 204

  Fly   257 RSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYI- 320
            |.||:|||||||....|:|:||||.||||.||||||||.||.:....||||:||||...||||:
Human   205 REGLVRARLLGASAARGDVLTFLDCHCECHEGWLEPLLQRIHEEESAVVCPVIDVIDWNTFEYLG 269

  Fly   321 TASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMD 385
            .:.:...|||:|:|.|.|:.||.||..|..:. ...:|:||||||||::.|.||..:||||.||:
Human   270 NSGEPQIGGFDWRLVFTWHTVPERERIRMQSP-VDVIRSPTMAGGLFAVSKKYFEYLGSYDTGME 333

  Fly   386 IWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKE 450
            :|||||||.|||:|.||||||..|||.|||||.|..||:......     |:.|..|||:|::||
Human   334 VWGGENLEFSFRIWQCGGVLETHPCSHVGHVFPKQAPYSRNKALA-----NSVRAAEVWMDEFKE 393

  Fly   451 FYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDY-YYLGEIRN-AETETC 513
            .||...|.||....|||::||.|||:|:||.|:|:||.||||..:|.|. .:.|.::| ..|:.|
Human   394 LYYHRNPRARLEPFGDVTERKQLRDKLQCKDFKWFLETVYPELHVPEDRPGFFGMLQNKGLTDYC 458

  Fly   514 LDTMGRKYNEKVG---ISY-CHGLGGNQVFAYTKRQQIM----SDDLCLDASSSNGPVNMVRCHN 570
            .|......|:.||   |.| |||:|.||.|.||.:::|.    ..:.|:...:....:.|..|..
Human   459 FDYNPPDENQIVGHQVILYLCHGMGQNQFFEYTSQKEIRYNTHQPEGCIAVEAGMDTLIMHLCEE 523

  Fly   571 MG-GNQEWVYDAEEKWIRHTNTGQCLQRATRD--DANTPLLRPCSYGKGQQWLMESK 624
            .. .||:::.. |:..:.|..:.:|:|.|.::  |:..||||.|:....|:|..:.:
Human   524 TAPENQKFILQ-EDGSLFHEQSKKCVQAARKESSDSFVPLLRDCTNSDHQKWFFKER 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	162/300 (54%)
		Ricin_B_lectin	503..619	CDD:395527	37/127 (29%)
GALNT12	NP_078918.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..67
		WcaA	134..429	CDD:223539	163/301 (54%)
		Catalytic subdomain A	135..244		65/109 (60%)
		pp-GalNAc-T	139..433	CDD:133004	162/300 (54%)
		Catalytic subdomain B	304..366		42/61 (69%)
		Ricin_B_lectin	445..574	CDD:279046	37/129 (29%)
		RICIN	447..576	CDD:238092	38/129 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750