DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and GALNT14

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_016860395.1	Gene:	GALNT14 / 79623	HGNCID:	22946	Length:	563	Species:	Homo sapiens

Alignment Length:	491	Identity:	217/491 - (44%)
Similarity:	294/491 - (59%)	Gaps:	26/491 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 EKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVIN 212
            :.:|...||...|:.||.||::.|.||..|....|.:.||.|||:|.|||||.:|||||:.||:|
Human    83 DPYKLYAFNQRESERISSNRAIPDTRHLRCTLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLN 147

  Fly   213 RSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVIT 277
            |:|..|::|||||||.|......|||    .||| |...||..:|.||:|:|:.||:...|..:|
Human   148 RTPTHLIREIILVDDFSNDPDDCKQL----IKLP-KVKCLRNNERQGLVRSRIRGADIAQGTTLT 207

  Fly   278 FLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVP 342
            |||:|||....||:|||.|:.::...||||:||:|:.:||.||.::....|||:|.|:|:|.::.
Human   208 FLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFTYIESASELRGGFDWSLHFQWEQLS 272

  Fly   343 SREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEI 407
            ..:.||| .|.|.|:|||.:|||||.|||.:|..:|.||..||||||||.|:|||||||||.|||
Human   273 PEQKARR-LDPTEPIRTPIIAGGLFVIDKAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEI 336

  Fly   408 APCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASAGDVSDRKA 472
            .|||||||||||..||.||.|.......|..|..|||:|::|::||:..|.|.:...|:|..|..
Human   337 VPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERPFGNVESRLD 401

  Fly   473 LRDRLKCKSFRWYLENVYPESLMPLD-YYYLGEIRNAETETCLDTMGRKYNEK---VGISYCHGL 533
            ||..|:|:||:|||||:|||..:|.: ....|.||  :.:.||::. |:.|::   :.:|.|..:
Human   402 LRKNLRCQSFKWYLENIYPELSIPKESSIQKGNIR--QRQKCLESQ-RQNNQETPNLKLSPCAKV 463

  Fly   534 GG----NQVFAYTKRQQIMSDDLCLDASS--SNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTG 592
            .|    :||:|:|..|||:.::|||...:  ...||.:|.|.|....|:|......  |.|..:.
Human   464 KGEDAKSQVWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKTGSH--IEHIASH 526

  Fly   593 QCLQRATRDDANTP----LLRPC-SYGKGQQWLMES 623
            .||......|....    ::.|| |....|.|.|.|
Human   527 LCLDTDMFGDGTENGKEIVVNPCESSLMSQHWDMVS 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	158/299 (53%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	36/129 (28%)
GALNT14	XP_016860395.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750