DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt4

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001072705.1	Gene:	galnt4 / 780162	XenbaseID:	XB-GENE-5803663	Length:	582	Species:	Xenopus tropicalis

Alignment Length:	549	Identity:	232/549 - (42%)
Similarity:	324/549 - (59%)	Gaps:	48/549 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KKWFLAPSVQEAKGK----------------PGEMGKPVKI---PADMKDLMKEKFKENQFNLLA 159
            ::|....::.|.|.:                |||.||..::   |.: |.:..|..::...|:..
Frog    47 RRWERVITLAEEKNEELRQPVYKKPPPDPNMPGEWGKAARLELGPTE-KKMQDESIEKYALNIYL 110

  Fly   160 SDMISLNRSLTDVRHEGCRRKHY-ASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEII 223
            ||.|||:|.:.|.|...|:.|.: ..||||||:||.|:|||.:|||||:.||:..||..||:|||
Frog   111 SDQISLHRHIMDNRMYECKSKTFNYRKLPTTSVVIAFYNEALSTLLRTIHSVLETSPAVLLREII 175

  Fly   224 LVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEG 288
            ||||.|::.:|..|||:|:..|. :..::||.||.||:|||::||.:..|:|:||||.||||..|
Frog   176 LVDDFSDKVYLKSQLEDYIGGLD-RVRLIRTTKREGLVRARIIGATYAIGDVLTFLDCHCECISG 239

  Fly   289 WLEPLLARIVQNRRTVVCPIIDVISDETFE-YITASDSTWGGFNWKLNFRWYRVPSREMARRNND 352
            ||||||.||.:|...||||:||.|...||| |:...:...|||:|:|.|:|:.||.:|..||.:
Frog   240 WLEPLLQRIGENETAVVCPVIDTIDWNTFEFYMQTGEPMIGGFDWRLTFQWHAVPEKERQRRKS- 303

  Fly   353 RTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVF 417
            |..|:|:||||||||::.|.||..:|:||.||::|||||||:|||||.|||.|||.|||.|||||
Frog   304 RIDPIRSPTMAGGLFAVSKKYFEYLGTYDMGMEVWGGENLELSFRVWQCGGTLEIEPCSHVGHVF 368

  Fly   418 RKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASAGDVSDRKALRDRLKCKSF 482
            .|..||..|.     ...|.||..|||:|.:||.:|:..|.|||.:.||:|:||.||:||:||||
Frog   369 PKKAPYARPN-----FLQNTARAAEVWMDGYKELFYNRNPPARKENYGDISERKLLRERLQCKSF 428

  Fly   483 RWYLENVYPESLMPLDY-YYLGEIRN-AETETCLDTMGRKYN---EKVGISYCHGLGGNQVFAYT 542
            .|||:||:|:..:|.|. .:.|.:|: ..:..|||.....:|   ..:.:..|||.||||.|.||
Frog   429 DWYLKNVFPDLHIPEDRPGWHGAVRSMGISNECLDYNAPDHNPTGAHLSLFGCHGQGGNQFFEYT 493

  Fly   543 KRQQIMSD---DLCLDASSSNGPVNMVRCHNMGG----NQEWVYDAEEKWIRHTNTGQCLQRATR 600
            ..::|..:   :||.:.......:.|:.|...|.    |..|.: ..:..|.|.::|.|:.....
Frog   494 TMREIRFNSVTELCAEVPEQQTYIGMMHCPKDGNPVPKNIAWEF-RNDGTIYHPSSGTCISSYRT 557

  Fly   601 DDANTPL-LRPCS-YGKGQQWLMESKFKW 627
            .:....: ::.|. ..|.|.|    ||:|
Frog   558 SEGRADVQMKGCDPSDKNQLW----KFEW 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	166/300 (55%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	31/128 (24%)
galnt4	NP_001072705.1	pp-GalNAc-T	142..436	CDD:133004	166/300 (55%)
galnt4	NP_001072705.1	Ricin_B_lectin	450..578	CDD:395527	31/128 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920