Protein Alignment Pgant5 and GALNT11

DIOPT Version :9

• Sequence 1: NP_001036338.1
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001358393.1
• Gene: GALNT11 / 63917
• HGNCID: 19875
• Length: 667
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 223/507 - (43%)
• Similarity: 319/507 - (62%)
• Gaps: 41/507 - (8%)

  Fly   109 PSVVLKKWFLAPSVQ---EAKGKPGEMGKPVKIPADMKDLMKEK--------FKENQFNLLASDM 162
            ||.||:..|.|..:.   :::.:..|.|. :|..:::..:..|:        ::::.||:|.||.
Human    63 PSRVLEPQFKANKIDDVIDSRVEDPEEGH-LKFSSELGMIFNERDQELRDLGYQKHAFNMLISDR 126

  Fly   163 ISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDD 227
            :..:|.:.|.|:..|:.|.|...||..|:||.|:|||::.|||||.|||:|:|..||.|||||||
Human   127 LGYHRDVPDTRNAACKEKFYPPDLPAASVVICFYNEAFSALLRTVHSVIDRTPAHLLHEIILVDD 191

  Fly   228 ASERDFLGKQLEEYVAK-LPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLE 291
            .|:.|.|..:|:|||.| ||.|..|:|..||.||||.|::||.|.:|||:.|||:|||....||:
Human   192 DSDFDDLKGELDEYVQKYLPGKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQ 256

  Fly   292 PLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAP 356
            ||||.|.::|.|||||:||:||.:|..| ::|....|||||.|:|:|..||..|:.|... .|||
Human   257 PLLAAIREDRHTVVCPVIDIISADTLAY-SSSPVVRGGFNWGLHFKWDLVPLSELGRAEG-ATAP 319

  Fly   357 LRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKST 421
            :::||||||||::::.||:|:|.||.|||||||||||:|||:|||||.|.|.|||||||:|||..
Human   320 IKSPTMAGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRR 384

  Fly   422 PYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYL 486
            ||..|.| .:.:.||:.||..||||::||.|:|..|..:..|.|::|:|..||.:|.||||:|||
Human   385 PYGSPEG-QDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSYGNISERVELRKKLGCKSFKWYL 448

  Fly   487 ENVYPESLM------PLDYYYL------------GEIRNAETETCLDTMGRKYNEKVG---ISYC 530
            :|||||..:      |....::            |.:.:.:|..||...||. ::|.|   :..|
Human   449 DNVYPEMQISGSHAKPQQPIFVNRGPKRPKVLQRGRLYHLQTNKCLVAQGRP-SQKGGLVVLKAC 512

  Fly   531 HGLGGNQVFAYTKRQQ-IMSDDLCLDASS--SNGPVNMVRCHNMGGNQEWVY 579
            .....||::.|.:..: :::..||||.|.  |:.|..:::||..||:|:|.:
Human   513 DYSDPNQIWIYNEEHELVLNSLLCLDMSETRSSDPPRLMKCHGSGGSQQWTF 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	170/300 (57%)
		Ricin_B_lectin	503..619	CDD:395527	25/83 (30%)
GALNT11	NP_001358393.1	Catalytic subdomain A	150..261		65/110 (59%)
		pp-GalNAc-T	154..452	CDD:133004	170/300 (57%)
		Catalytic subdomain B	319..381		43/61 (70%)
		Ricin_B_lectin	483..>564	CDD:366226	25/81 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750