DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt1

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_031759269.1	Gene:	galnt1 / 594943	XenbaseID:	XB-GENE-1013398	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	606	Identity:	357/606 - (58%)
Similarity:	420/606 - (69%)	Gaps:	61/606 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 CRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEK 83
            |::||.||||||..|..|:..:|:|.     :|                       ||.:   |:
Frog     7 CKVVLATSLVWVFLDMFLLLYFSECN-----KC-----------------------DDKK---ER 40

  Fly    84 SLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSV-QEAKGKPGEMGKPVKIPADMKDLMK 147
            .|.|..|                             |.: |:....||||||||.||.:.::.||
Frog    41 GLPGGDG-----------------------------PDINQKPHEGPGEMGKPVVIPKEEQEKMK 76

  Fly   148 EKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVIN 212
            |.||.|||||:||:||:|||||.|||.|||:.|.|...|||||:||||||||||||||||.||||
Frog    77 EMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVIN 141

  Fly   213 RSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVIT 277
            ||||.||:|||||||||||:||.:.||.||.||.|...|||.|:|||||||||.||....|:|||
Frog   142 RSPRHLLQEIILVDDASEREFLKRPLETYVKKLTVPVHVLRMEQRSGLIRARLRGAAASKGQVIT 206

  Fly   278 FLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVP 342
            |||||||||.||||||||||..:||||||||||||||:||||:..||.|:||||||||||||.||
Frog   207 FLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVP 271

  Fly   343 SREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEI 407
            .|||.||..|||.|:|||||||||||||:|||.|||:||.|||||||||||:|||:|.|||.|||
Frog   272 QREMDRRRGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEI 336

  Fly   408 APCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASAGDVSDRKA 472
            ..||.|||||||:|||||||||.:|:|.||.||.|||:|::|.|:|...||..|...||:|.|..
Frog   337 VTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRVG 401

  Fly   473 LRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQ 537
            ||.:|:||.|.||||||||:|.:|..||.||||||.||..|||.|.||.||||||..|||:||||
Frog   402 LRHKLQCKPFSWYLENVYPDSQIPRHYYSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQ 466

  Fly   538 VFAYTKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDD 602
            ||:||..::|.:||||||.|..||||.|::||::.|||.|.||..:..:.|.|:.|||.:|..:|
Frog   467 VFSYTASKEIRTDDLCLDVSKLNGPVIMLKCHHLRGNQLWEYDPVKLTLVHVNSNQCLDKAAEED 531

  Fly   603 ANTPLLRPCSYGKGQQWLMES 623
            :..|.:|.||..:.||||:.:
Frog   532 SQVPSIRDCSGSRSQQWLLRN 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	220/299 (74%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	63/115 (55%)
galnt1	XP_031759269.1	pp-GalNAc-T	119..419	CDD:133004	220/299 (74%)
galnt1	XP_031759269.1	Ricin_B_lectin	432..548	CDD:395527	63/115 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	294	1.000	Domainoid score	I1475
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8469
Inparanoid	1	1.050	669	1.000	Inparanoid score	I741
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194016at33208
OrthoFinder	1	1.000	-	-		FOG0002015
OrthoInspector	1	1.000	-	-		otm48271
Panther	1	1.100	-	-	LDO	PTHR11675
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2292
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160