DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant5 and CG10000

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	496	Identity:	160/496 - (32%)
Similarity:	256/496 - (51%)	Gaps:	43/496 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 QFNLLASDMISLNRSLTDVRHEGCRRKHYASKLP-----TTSIVIVFHNEAWTTLLRTVWSVINR 213
            |:|:..|:.:.|.|.|...||..|..::  |.||     ..|:||.|||||.:.||||:.|:::|
  Fly    74 QYNIHLSNALGLIRKLPVTRHHSCTTRN--SILPAPLEANVSVVISFHNEARSMLLRTIVSLLSR 136

  Fly   214 SPRALLKEIILVDDASERDF-LGKQLEEYV-----AKLPVKTFVLRTEKRSGLIRARLLGAEHVS 272
            ||...|.|:|||||.|:||. |...|:.::     ::..:....||.::|.|||.:|..||...|
  Fly   137 SPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLAS 201

  Fly   273 GEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFR 337
            |..:.|||:|||..||||||||.|:..|....|.|::|.|...|..|...::...|||:|.|:|.
  Fly   202 GRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFH 266

  Fly   338 WYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCG 402
            |.:   |::..:.: ...|.::|..|||:..:.:::|.::||::..:.|||||::|::.::|:||
  Fly   267 WLK---RQLTNQES-LEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCG 327

  Fly   403 GVLEIAPCSRVGHVFRKSTPYTFP-------GGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGAR 460
            |.:||.||||:||:||:...:.||       ....|...||:..:.|.|||::|..:|:..|.||
  Fly   328 GQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAAR 392

  Fly   461 KASAGDVSDR-KALRDRLKCKSFRWYLENVYPESLMPLD-YYYLGEIRNAETETCLDTMGRKYNE 523
            :.......|. :.:|...:|..|.|||.:|.||..|..| ....|.:||  .:.|:.  .|:.:.
  Fly   393 RIPLDHTYDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRN--EDRCVH--ARQKDS 453

  Fly   524 KVGISYCHGLGGNQVFAYTKRQQIMSD-DLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIR 587
            :..::.|:.....|.....:..|:.:. :||| |......:.:..|    |..|.| ...::|:|
  Fly   454 QPILASCYLSDITQWSMLRQSGQLSTHRELCL-AVGFGMRIALEPC----GRNETV-RRSQRWVR 512

  Fly   588 ------HTNTGQCLQRATRDDANTPLLRPCSYGKGQQWLME 622
                  |..:..||....:|.......|..:..:..|:.:|
  Fly   513 LGTHLLHAESHLCLDNPLKDRLEMSTCRSHAVSQSFQFALE 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	118/313 (38%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	23/122 (19%)
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	118/312 (38%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	23/122 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920