DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt6

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_998361.1	Gene:	galnt6 / 406477	ZFINID:	ZDB-GENE-040426-2272	Length:	619	Species:	Danio rerio

Alignment Length:	542	Identity:	251/542 - (46%)
Similarity:	322/542 - (59%)	Gaps:	44/542 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 YPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQ-------FNLLASDMISL 165
            |....||.|...|  .|....||..|    :|.....:.||:.||.|       ||..|||.|||
Zfish    89 YTQRELKPWIERP--PENPQAPGADG----VPFQYDRMTKEEEKEKQEGMTRHCFNQFASDRISL 147

  Fly   166 NRSL-TDVRHEGC--RRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDD 227
            :|:| .|.|...|  |:......|||||::||||||||:||||||:||::.||.|.|||||:|||
Zfish   148 HRTLGDDTRPPECVDRKFRRCPALPTTSVIIVFHNEAWSTLLRTVYSVLHTSPAAFLKEIIMVDD 212

  Fly   228 ASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEP 292
            ||..:.|..:|||||..|.: ..|:|..:|.|||.||||||....||::|||||||||..|||||
Zfish   213 ASTAEHLHGKLEEYVKALKI-VKVVRQPERKGLITARLLGASKAEGEILTFLDAHCECFHGWLEP 276

  Fly   293 LLARIVQNRRTVVCPIIDVISDETFEY----ITASDSTWGGFNWKLNFRWYRVPSREMARRNNDR 353
            ||||||:....||.|.|..|...||::    .||.....|.|:|.|.|.|..:|..|.|:| .|.
Zfish   277 LLARIVEEPTAVVSPEITTIDLNTFQFHKPVATARAHNRGNFDWSLTFGWEGIPDYENAKR-KDE 340

  Fly   354 TAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFR 418
            |.|::|||.|||||||.|.||.:||:||:.|:||||||:|||||||.|||.|||.|||.||||||
Zfish   341 TYPVKTPTFAGGLFSISKAYFEKIGTYDDKMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFR 405

  Fly   419 KSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYY----SFYPGARKASAGDVSDRKALRDRLKC 479
            ..:|:|||.| ||::..|..||.|||:||:|..:|    |....|::...||:|||..||:.|:|
Zfish   406 TKSPHTFPKG-TEVITRNQVRLAEVWMDDYKLIFYRRSQSAAKMAKEKGFGDISDRLKLREDLQC 469

  Fly   480 KSFRWYLENVYPESLMP-LDYYYLGEIRNAETETCLDTMGRKYNEKVGISY-CHGLGGNQVFAYT 542
            |:|.|||.|||||:.:| |.....|.::|...:.|||........|..|.| ||.:||||.|.||
Zfish   470 KNFSWYLSNVYPEAFVPDLSPVKFGALKNRGAQQCLDVGESNNGGKPVIMYTCHNMGGNQYFEYT 534

  Fly   543 KRQQI---MSDDLCLDASSSNGPVNMVRC------HNMGGNQEWVYDAEEKWIRHTNTGQCLQRA 598
            ..:::   :...|||.||....||.:..|      .::...|||:. .||:.:::.::|:||.:
Zfish   535 SHKELRHNIGKQLCLQASPYPEPVKIELCTLKGKGSSLAPEQEWLI-TEEQLLKNPSSGKCLHK- 597

  Fly   599 TRDDANTPLLRPCS-YGKGQQW 619
               ..:..|:.||: ....|||
Zfish   598 ---KGDKILMSPCNPDDHHQQW 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	173/307 (56%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	37/126 (29%)
galnt6	NP_998361.1	pp-GalNAc-T	175..480	CDD:133004	173/307 (56%)
		Ricin_B_lectin	493..616	CDD:279046	37/127 (29%)
		RICIN	494..618	CDD:238092	39/128 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850