DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant5 and CG7304

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	160/560 - (28%)
Similarity:	258/560 - (46%)	Gaps:	92/560 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 FASGGISMTYPSVVLKKW------FLAPSVQEAKGKPGEMGKP----------VKIPADMKDLMK 147
            ||| .::..:..:||..|      .|...:....|..|.:..|          :.:|:...|...
  Fly     4 FAS-VLNCCFKYIVLPVWIFIVLLLLHRDLSSWDGLMGPLSHPGLGENGSASYLSVPSWEIDEYT 67

  Fly   148 EKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHY---ASKLPTTSIVIVFHNEAWTTLLRTVWS 209
            :.::...:|...::.|.|.|||.|:|...|::..|   :.::...||:::|.||....||||:.|
  Fly    68 QGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHS 132

  Fly   210 VINRSPRALLKEIILVDDASERDFLGKQL-----EEYVAK-LPVKTFVLRTEKRSGLIRARLLGA 268
            ::.|:|:.|..|:|||:|.|:.||...:|     :.||.: :..|..:|...::.|||:||.|.|
  Fly   133 LVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAA 197

  Fly   269 EHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWK 333
            .....|.:.|:||..|.|.|||.|||..|.:...|:..||:|.:.::|..| ..|....|.::|.
  Fly   198 SEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAY-QRSIERRGMYDWS 261

  Fly   334 LNFRWYRVP-SREMARRNN----DRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLE 393
            |..|  .|| ||  |||::    ...|.:||     .:|:|...:|.:|.::|..:..:|...||
  Fly   262 LTRR--EVPLSR--ARRSHLPWPYEVAAVRT-----SVFAIPAVWFQDISNFDNNLRGFGAAELE 317

  Fly   394 MSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTT----EIVNHNNARLVEVWLDDWKEFYYS 454
            :||:||..||.:...|||||||:..|...|....|..    |..:.|..|::|||..|.|...|.
  Fly   318 LSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYK 382

  Fly   455 FYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYP-----ESLMPLDYYYLGEIRNAE-TETC 513
            :.|.....|.||:::.:.|..:.:|:||:.::.::.|     .:|...| |..|.::..| .:.|
  Fly   383 YQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTD-YASGHVKTLEFPKKC 446

  Fly   514 LDTMGRKY-------------------------------------NEKVGISYCHGLGGNQVFAY 541
            | |:..|.                                     |.::|.|:||.|||.|.:.|
  Fly   447 L-TINAKSQNLFLERCSTNNTLQNWTLTYVKDLRVAGNICAEVRPNLRLGYSFCHSLGGRQSWHY 510

  Fly   542 -TKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYD 580
             :...|:||:..||:.:.... :.:..|....|.|.|:.|
  Fly   511 DSVSNQLMSNTKCLEFTDELN-IFLAICDAANGKQRWILD 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	108/314 (34%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	26/117 (22%)
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	46/122 (38%)
		pp-GalNAc-T	113..417	CDD:133004	108/313 (35%)
		Ricin_B_lectin	433..546	CDD:279046	24/114 (21%)
		RICIN	435..548	CDD:238092	25/114 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840