DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant5 and Pgant6

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster

Alignment Length:	603	Identity:	226/603 - (37%)
Similarity:	335/603 - (55%)	Gaps:	74/603 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 EYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYP--SVVLKKW-- 116
            |.|.||    :.:|:.:.|:: |::.....|.|.       |......:.|..|  :.|.|.|
  Fly    78 EEDPEL----QKIDEPEPVEE-EVDNPHPADDEP-------QQQPQEELQMAAPADASVKKDWHD 130

  Fly   117 --FLAPSVQEAKGKP-GEMGKPVKIPAD-MKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGC 177
              |:.   ::||... ||.||...:..: .:||.|....||.||.|.||.||:|||:.|:||..|
  Fly   131 YTFME---KDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLC 192

  Fly   178 RRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYV 242
            |:|.|.:||||.|::|:|:||..:.|:|:|.|:|||||..|:||||||||.|:|::|||:||.|:
  Fly   193 RKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYI 257

  Fly   243 AKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCP 307
            |:......|:|..:|:|||.||..||.:.:.||:.|||:|.|....||.|||..|..|:||.|||
  Fly   258 AEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCP 322

  Fly   308 IIDVISDETFEYITASDSTWGGFNWKLNFRWYRVP-SREMARRNNDRTAPLRTPTMAGGLFSIDK 371
            .||||....|.|....:...|.|:|:  |.:.|:| ..|..:...|   |.::|.||||||:|.:
  Fly   323 FIDVIDHTNFHYRAQDEGARGAFDWE--FFYKRLPLLPEDLKHPAD---PFKSPIMAGGLFAISR 382

  Fly   372 DYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHN 436
            ::|:|:|.||||:||||||..|:||::|||||.:..|||||:||::|....:.......:.::.|
  Fly   383 EFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKN 447

  Fly   437 NARLVEVWLDDWKEFYYSFYPGA-RKASAGDVSDRKALRDRLKCKSFRWYLENV-------YPES 493
            ..|:.|||:|::|.:.||...|. .....||::::||:|.:|.||||:|::|.|       ||
  Fly   448 YKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP-- 510

  Fly   494 LMPLD--YYYLGEIRNAETET-CLDTMGRKYNEKVGISYCHGLGGNQV----------FAYTKRQ 545
              |:|  .|.:|.::|...:. ||||:|||.:.|:|:..|    .:.:          .::.:..
  Fly   511 --PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYAC----ADNIKTPQRTQFWELSWKRDL 569

  Fly   546 QIMSDDLCLDAS--SSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTG-QCL------QRATRD 601
            ::.....|||..  .:|.||.:..||:.||||.|.||...|.::|...| :||      |....:
  Fly   570 RLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQEVVAN 634

  Fly   602 DANTPLLRPCSYGKGQQW 619
            ..:|.       .:.|||
  Fly   635 KCDTD-------NRFQQW 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	136/308 (44%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	35/135 (26%)
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	106/218 (49%)
		pp-GalNAc-T	205..502	CDD:133004	135/301 (45%)
		RICIN	520..647	CDD:238092	37/137 (27%)
		Ricin_B_lectin	520..645	CDD:279046	35/135 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457049
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60373at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850