DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant5 and Pgant1

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster

Alignment Length:	527	Identity:	219/527 - (41%)
Similarity:	304/527 - (57%)	Gaps:	35/527 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 VQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYAS-K 185
            :|:.|...||.|..|.:....|:...|.:|:...|...|:.::.|||:.|.|:..|.::.:.| .
  Fly    83 LQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDS 147

  Fly   186 LPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYV-AKLPV-K 248
            |||.|:||:|.||.::.|||||.|.::......|||||||||.|:...||.:|:.|| .::|. |
  Fly   148 LPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGK 212

  Fly   249 TFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVIS 313
            ..:||.:.|.|||||||.||...:|:|:.|||||||...||.||||.||.::|.:|:.||||||.
  Fly   213 VTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVID 277

  Fly   314 DETFEYITASDSTW--GGFNWKLNFRWYRVPSREMARRNND-----RTAPLRTPTMAGGLFSIDK 371
            ...|:|.|....::  |||.|..:|.|..:|.||..|:..:     ...|..:||||||||:||:
  Fly   278 ANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDR 342

  Fly   372 DYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNH- 435
            .||:|:|||||.||.|||||||||||:|.|||.:|..|||||||:||...||.||....   .|
  Fly   343 RYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRD---THG 404

  Fly   436 -NNARLVEVWLDDWKEFYYSFYPGAR-KASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPL- 497
             |.||:..||:|::...::...|..: .|..|||:.|..||.:|:||||.|||:|:|||..:|.
  Fly   405 INTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTK 469

  Fly   498 DYYYLGEIRNAETETCLDTMGRKYNEK---VGISYC-HGLGGNQVFAYTKRQQIMSDDLCLDASS 558
            |....|::....:..|||.: .:.|||   .|:..| ..|..:|:|::|....:.::..|.....
  Fly   470 DVQGWGKVHAVNSNICLDDL-LQNNEKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQH 533

  Fly   559 SNGP---VNMVRC-HNMGGNQEWVYDAEEKWIRHTNTGQCLQR---ATRDDANTPLLRPCS-YGK 615
            |..|   |.||.| .|...|::|.|  |.:.|.|:|||.||..   .:.|||.   :.||. :.:
  Fly   534 SESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLDHQGLKSLDDAQ---VAPCDPHSE 593

  Fly   616 GQQWLME 622
            .|:|.:|
  Fly   594 SQRWTIE 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	153/311 (49%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	38/127 (30%)
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	139/281 (49%)
		pp-GalNAc-T	152..461	CDD:133004	153/311 (49%)
		Ricin_B_lectin	474..597	CDD:279046	38/128 (30%)
		RICIN	481..599	CDD:238092	38/123 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25604at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920