Protein Alignment Pgant5 and Galntl6

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001129228.1
• Gene: Galntl6 / 361142
• RGDID: 1564773
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 220/537 - (40%)
• Similarity: 311/537 - (57%)
• Gaps: 46/537 - (8%)

  Fly   114 KKWFLAPSVQE---AKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHE 175
            |.|....|:|:   ..|| ||.|||  .|...:|.....::||.||:..|:.|:|.|||.|:||.
  Rat    67 KDWHDYVSIQKDALRSGK-GEHGKP--YPLTEEDHDDSAYRENGFNIFVSNNIALERSLPDIRHA 128

  Fly   176 GCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEE 240
            .|:.|.|..:||.|||:|.||||.||:||||:.|:|||:|.:|:.|||||||.|:|:.|..:||:
  Rat   129 NCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDKLED 193

  Fly   241 YVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVV 305
            |:|:.|: ..::||:||.||||.|||||....|||:||||:|||....||.|||.:|..|.:|:|
  Rat   194 YMARFPI-VRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIV 257

  Fly   306 CPIIDVISDETFEY-ITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSI 369
            ||:||||....|.| ..|.|:..|.|:|::.::...:|. |:.|.  |.:.|..:|.||||||::
  Rat   258 CPMIDVIDHSHFGYEAQAGDAMRGAFDWEMYYKRIPIPP-ELQRA--DPSEPFESPVMAGGLFAV 319

  Fly   370 DKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVL 434
            |:.:|:|:|.||.|::|||||..|:||::|.|||.:..:|||.|||::|...||..|.|.:  :.
  Rat   320 DRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPSGTS--LA 382

  Fly   435 HNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFRWYLENV-------YPE 492
            .|..||||.|:||:.::.|......|..|.||:|.:|.||.|||||.|:|::..|       ||
  Rat   383 RNLKRVAETWMDEFAEYIYQRRPEYRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYP- 446

  Fly   493 SLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGG------NQVFAYTKRQQIMSDD 551
            .:.||...: |||||.....|:|:.......::.:..|...|.      .|:|.:..|:.|...:
  Rat   447 PVEPLPAAW-GEIRNVAANLCVDSKHGAMGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGE 510

  Fly   552 ------LCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTP---- 606
                  .||||.|.:.||.:..||.|.|||.|.| .|::.:.|..:..|:      |.|..
  Rat   511 PLHTRKFCLDAISHSSPVTLYDCHGMKGNQLWGY-REDRTLFHPVSNSCM------DCNPAEKKV 568

  Fly   607 -LLRPCSYGKGQQWLME 622
             :.|.....:.|||:.|
  Rat   569 FMARCDPLSETQQWMFE 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	146/307 (48%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	39/143 (27%)
Galntl6	NP_001129228.1	pp-GalNAc-T	143..438	CDD:133004	145/300 (48%)
		beta-trefoil_Ricin_GALNTL6	449..594	CDD:467355	40/145 (28%)