DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and Galnt11

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001258248.1	Gene:	Galnt11 / 311952	RGDID:	735097	Length:	609	Species:	Rattus norvegicus

Alignment Length:	508	Identity:	220/508 - (43%)
Similarity:	321/508 - (63%)	Gaps:	34/508 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 DMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLR 205
            :::||   .::::.||:|.|:.:..:|.:.|.|:..||.|.|.:.|||.|:||.|:|||::.|||
  Rat   109 ELRDL---GYQKHAFNMLISNRLGYHRDVPDTRNAECRGKSYPTDLPTASVVICFYNEAFSALLR 170

  Fly   206 TVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAK-LPVKTFVLRTEKRSGLIRARLLGAE 269
            ||.||::|:|..||.|||||||:|:.|.|..:|:||:.: ||.|..|:|..||.||||.|::||.
  Rat   171 TVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLPAKVKVIRNMKREGLIRGRMIGAA 235

  Fly   270 HVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKL 334
            |.:|||:.|||:|||....||:||||.|:::..|||||:||:||.:|..| ::|....|||||.|
  Rat   236 HATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAY-SSSPVVRGGFNWGL 299

  Fly   335 NFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVW 399
            :|:|..||..::...:: .|||:|:||||||||::::.||.::|.||.|||||||||||:|||:|
  Rat   300 HFKWDLVPVSDLGGADS-ATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIW 363

  Fly   400 MCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASA 464
            ||||.|.|.|||||||:|||..||..|.| .:.:.||:.||..||||::||.|:|..|..:..|.
  Rat   364 MCGGKLFIIPCSRVGHIFRKRRPYGSPEG-QDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSF 427

  Fly   465 GDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYL------------------GEIRNAETE 511
            |::|:|..||.:|.|:||:|||:|||||..:......|                  |.:.:.:|.
  Rat   428 GNISERVELRKKLGCQSFKWYLDNVYPEMQVSGPKARLQQPVFINRGPKRPRVLLRGRLYHLQTN 492

  Fly   512 TCLDTMGRKYNEKVG---ISYCHGLGGNQVFAYTKRQQ-IMSDDLCLDASS--SNGPVNMVRCHN 570
            .||...||. ::|.|   :..|......||:.|.:..: |:::.||||.|.  |:.|..:::||.
  Rat   493 KCLVAQGRS-SQKGGLVLLKACDYGDPTQVWIYNEEHELILNNLLCLDMSETRSSDPPRLMKCHG 556

  Fly   571 MGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPL-LRPCSYGKGQQWLME 622
            .||:|:|.:....: :...:.||||:...:.|....: :..|.....|||.:|
  Rat   557 SGGSQQWTFGKNNR-LYQVSVGQCLRVVDQMDQKGYVGMAICDGSSSQQWRLE 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	163/300 (54%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	33/122 (27%)
Galnt11	NP_001258248.1	pp-GalNAc-T	155..453	CDD:133004	163/300 (54%)
		Glyco_tranf_2_3	155..383	CDD:290369	130/229 (57%)
		Ricin_B_lectin	484..605	CDD:279046	33/122 (27%)
		RICIN	488..607	CDD:238092	34/120 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750