Protein Alignment Pgant5 and GALNT3

DIOPT Version :9

• Sequence 1: NP_001036338.1
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_004473.2
• Gene: GALNT3 / 2591
• HGNCID: 4125
• Length: 633
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 258/641 - (40%)
• Similarity: 345/641 - (53%)
• Gaps: 86/641 - (13%)

  Fly    30 VIFDFVLI---------ARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSL 85
            |||.|:::         .:||    |:..|.:|:      :.|..:::|   |:.:...|.:.::
Human    26 VIFFFIIVLVLMQREVSVQYS----KEESRMERN------MKNKNKMLD---LMLEAVNNIKDAM 77

  Fly    86 DGESGGALIMGQGFASGG---ISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMK 147
            .....||.:. |...:|.   :...|.:..||.....|  .:....||..||..|    ..:|..
Human    78 PKMQIGAPVR-QNIDAGERPCLQGYYTAAELKPVLDRP--PQDSNAPGASGKAFK----TTNLSV 135

  Fly   148 EKFKENQ-------FNLLASDMISLNRSL-TDVRHEGCRRKHY--ASKLPTTSIVIVFHNEAWTT 202
            |:.||.:       ||..|||.|||:|.| .|.|...|..:.:  ...|||||::||||||||:|
Human   136 EEQKEKERGEAKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWST 200

  Fly   203 LLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLG 267
            |||||.||:..||..||||||||||||..::|..:|:|||.:..: ..::|..:|.|||.|||||
Human   201 LLRTVHSVLYSSPAILLKEIILVDDASVDEYLHDKLDEYVKQFSI-VKIVRQRERKGLITARLLG 264

  Fly   268 AEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYIT----ASDSTWG 328
            |...:.|.:|||||||||..||||||||||.:|...||.|.|..|...|||:..    .|:...|
Human   265 ATVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHNRG 329

  Fly   329 GFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLE 393
            .|:|.|:|.|..:|..|..|| .|.|.|::|||.|||||||.|:||..||||||.|:||||||:|
Human   330 NFDWSLSFGWESLPDHEKQRR-KDETYPIKTPTFAGGLFSISKEYFEYIGSYDEEMEIWGGENIE 393

  Fly   394 MSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPG 458
            ||||||.|||.|||.|||.||||||..:|::||.| |:::..|..||.|||:|::||.:|.....
Human   394 MSFRVWQCGGQLEIMPCSVVGHVFRSKSPHSFPKG-TQVIARNQVRLAEVWMDEYKEIFYRRNTD 457

  Fly   459 ARK----ASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMP-LDYYYLGEIRNAETETCLDTMG 518
            |.|    .:.||:|.|..::.||:||:|.|||.|:|||..:| |:....|.|::.....|||...
Human   458 AAKIVKQKAFGDLSKRFEIKHRLQCKNFTWYLNNIYPEVYVPDLNPVISGYIKSVGQPLCLDVGE 522

  Fly   519 RKYNEKVGISY-CHGLGGNQVFAYTKRQQI---MSDDLCLDASSSNGPVNMVRCHNMGGNQEWVY 579
            .....|..|.| ||||||||.|.|:.:.:|   :..:|||.|  :.|.|.:..|...|  .:.|.
Human   523 NNQGGKPLIMYTCHGLGGNQYFEYSAQHEIRHNIQKELCLHA--AQGLVQLKACTYKG--HKTVV 583

  Fly   580 DAEEKWIRHTNTGQCLQRATRDDANTPLLRPCSYGKG--------------QQWLM 621
            ..|:.|  .....|.|.        .|.|:.|....|              |:|::
Human   584 TGEQIW--EIQKDQLLY--------NPFLKMCLSANGEHPSLVSCNPSDPLQKWIL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	168/307 (55%)
		Ricin_B_lectin	503..619	CDD:395527	37/133 (28%)
GALNT3	NP_004473.2	Catalytic subdomain A	184..293		68/109 (62%)
		pp-GalNAc-T	188..493	CDD:133004	168/307 (55%)
		Catalytic subdomain B	356..418		47/61 (77%)
		Ricin_B_lectin	506..627	CDD:306998	37/134 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850