Protein Alignment Pgant5 and Galnt18

DIOPT Version :9

• Sequence 1: NP_001036338.1
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_776100.2
• Gene: Galnt18 / 233733
• MGIID: 2446239
• Length: 622
• Species: Mus musculus
• Alignment Length: 678
• Identity: 220/678 - (32%)
• Similarity: 327/678 - (48%)
• Gaps: 135/678 - (19%)

  Fly     7 TRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPN--AERLVD 69
            |||.:..:  :||  |:|:.:..:|           |:...||           :.|  |...|.
Mouse     4 TRKTKTLV--STC--VILSGMTNII-----------CLLYVGW-----------VTNYIASVYVR 42

  Fly    70 DNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEM-G 133
            ..:.|.|      |.|:.:.|..|.:.:       .:.:...|:|:     .:|||..||.|. .
Mouse    43 GQEPVPD------KKLEEDKGDTLKIIE-------RLDHLENVIKQ-----HIQEAPAKPEEAEA 89

  Fly   134 KPV-----------KIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLP 187
            :|.           ::..:.:.:..::|:...:|...||.:.|:|.|.|:|..|||...:...||
Mouse    90 EPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLP 154

  Fly   188 TTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKL----PVK 248
            ..|||.:|.|||.:.|||::.|.:.|:|..||||||||||.|..:.|.::|.|||.|:    |..
Mouse   155 EVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGF 219

  Fly   249 TFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVIS 313
            ..|:|..|:.||||:|:.|....:..|:...|||.|...||.||:|.||.:||:.::.|..|.|.
Mouse   220 IKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIK 284

  Fly   314 DETF---EYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFY 375
            .:.|   ||..|:.    ||:|:|..|:...|.......|:  |||:|:|.:. |.|.:|:.||.
Mouse   285 YDNFEIEEYPLAAQ----GFDWELWCRYLNPPKAWWKLENS--TAPIRSPALI-GCFIVDRQYFE 342

  Fly   376 EIGSYDEGMDIWGGENLEMSFR---------------VWMCGGVLEIAPCSRVGHVFRKSTPYTF 425
            |||..||||:::||||:|:..|               ||.|||.:|:.||||:.|:.|...|||
Mouse   343 EIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVLPCSRIAHIERAHKPYT- 406

  Fly   426 PGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASA---GDVSDRKALRDRLKCKSFRWYLE 487
             ...|..|..|..|:.|||:|::|...|..:...::.|.   ||::.|||||.:|:||:|||||.
Mouse   407 -EDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLV 470

  Fly   488 NVYPESLMPLDYYYLGEIRNA-ETETCLDTMGRKYNEKVGISY-CHGLGGNQVFAYTKRQQIM-- 548
            :||||..|..|....|.::|: :|:.||| .|.. .|.|.|.| |||:....|: ||..|||.
Mouse   471 SVYPEMRMYSDIIAYGVLQNSLKTDLCLD-QGPD-TENVPIVYICHGMTPQNVY-YTSSQQIHVG 532

  Fly   549 --------SDDLCL-DASS-------SNGPVNMVRCH---NMGGNQEWVYDAEEKWIRHTNTGQC 594
                    .|:.|| |.:|       |......::.|   :.||:           |::..:.:|
Mouse   533 ILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGS-----------IQNRKSKRC 586

  Fly   595 LQRATRDDAN---TPLLRPCSYGKGQQW 619
            |:.....|..   ..:|:.||   ||.|
Mouse   587 LELQENSDMEFGFQLVLQKCS---GQHW 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	132/324 (41%)
		Ricin_B_lectin	503..619	CDD:395527	38/141 (27%)
Galnt18	NP_776100.2	Catalytic subdomain A	153..267		52/113 (46%)
		pp-GalNAc-T	157..473	CDD:133004	132/324 (41%)
		Catalytic subdomain B	324..400		32/76 (42%)
		Ricin_B_lectin	484..611	CDD:279046	38/143 (27%)
		RICIN	486..613	CDD:238092	39/143 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842588
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740