DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant5 and gly-11

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001022948.1	Gene:	gly-11 / 176647	WormBaseID:	WBGene00001636	Length:	605	Species:	Caenorhabditis elegans

Alignment Length:	644	Identity:	230/644 - (35%)
Similarity:	338/644 - (52%)	Gaps:	84/644 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQ---LVDD 76
            |..|..::.|.|::..|  ::.::.|.:    |..|...||..|::..: |:|.:..|   ..||
Worm     6 RRKTVGLICLFSILLTI--YLYVSMYPE----DNERVWNSGNADIQRKH-EKLNNGGQGRHDFDD 63

  Fly    77 NEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPAD 141
            :|                        |........|.|:...||.:.::.....:..|.::|..|
Worm    64 DE------------------------GAEKDEEDAVEKQNIAAPPLPKSFTTFPDRSKEIEIDTD 104

  Fly   142 M---------KDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHN 197
            :         .||..|.:|:.|||.|.||.|...|.:.|.|:..|....|:..||..|||:.:.|
Worm   105 LLGKINGKAEDDLQVEGYKKYQFNGLLSDRIGSRRKIKDSRNARCSSLTYSDSLPAASIVVCYFN 169

  Fly   198 EAWTTLLRTVWSVINRSPRALLKEIILVDDASE----RDFLGKQLEEYVAKLPVKTFVLRTEKRS 258
            |:.:.|:|.|.|:.:|:....|.||:||||:||    .|...|..|:::.:.. |...|:|:|..
Worm   170 ESPSVLIRMVNSIFDRTKPEHLHEILLVDDSSEWSNATDEAIKYREKHIIQWE-KVKFLKTDKNE 233

  Fly   259 GLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITAS 323
            |||||::.||...:|||:.|||:|||..|.||.|||.:|.||||.|||||||:|...|.:|:.:.
Worm   234 GLIRAKIFGARRANGEVLVFLDSHCEVNEEWLPPLLDQIKQNRRRVVCPIIDIIDAITMKYVESP 298

  Fly   324 DSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWG 388
            ..| ||.||.:.|:| ..|.|.......:...||::||||||||:|||:||:||||||||||:||
Worm   299 VCT-GGVNWAMTFKW-DYPHRSYFEDPMNYVNPLKSPTMAGGLFAIDKEYFFEIGSYDEGMDVWG 361

  Fly   389 GENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYY 453
            .||:|:|.|:|.|||.|.|.|||||||:||:..||   |..|:.:..|:.||..||||::.|.::
Worm   362 AENVEISVRIWTCGGELLIMPCSRVGHIFRRQRPY---GIKTDSMGKNSVRLARVWLDEYLENFF 423

  Fly   454 SFYPGARK-ASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMP-------------LDYYYLGE 504
            ...|..|. ...||::.|.:||..|:||.|:|||||:||| |:|             ....||
Worm   424 EARPNYRTFTDYGDLTSRISLRRNLQCKPFKWYLENIYPE-LLPDNTPNQLNNQILVAGKKYL-- 485

  Fly   505 IRNAETETCL---DTMGRKYN-EKVGISYCHGLGGNQVFAYTKRQQIM---SDDLCLDASSSNGP 562
            |:.|....||   ::.||..| .:|.:..|:.:...|.:.|:...::.   |..:|||  |..|
Worm   486 IKMANGTHCLSAENSQGRIANGNRVEMRKCNHMERMQQWKYSSTNELRPMGSSRMCLD--SLRG- 547

  Fly   563 VNMVRCHNMGGNQEW-VYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPCSYGKGQQWL 620
            ::::.|||.|.:|.| |.:|.:.:.|..|  :| ...:.|.:....|:.||.....|::
Worm   548 ISVILCHNQGAHQMWQVSNAGKLYSRSVN--KC-ATGSNDVSALSTLKFCSLANSFQFV 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	147/304 (48%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	32/123 (26%)
gly-11	NP_001022948.1	pp-GalNAc-T	162..461	CDD:133004	147/304 (48%)
		Glyco_tranf_2_3	162..392	CDD:290369	118/232 (51%)
		RICIN	484..599	CDD:238092	34/122 (28%)
		Ricin_B_lectin	486..602	CDD:279046	32/121 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920