DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and gly-8

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001366981.1	Gene:	gly-8 / 176595	WormBaseID:	WBGene00001633	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	147/379 - (38%)
Similarity:	229/379 - (60%)	Gaps:	25/379 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 LAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHY 182
            |..::.||:.|..|.|                .|...|:.|:|:.:..||::....|:.|..:.|
Worm    55 LKENLTEAESKKSEWG----------------IKSFAFDALSSEKLGPNRNVGKQAHKLCEEEKY 103

  Fly   183 ASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERD-FLGKQLEEY--VAK 244
            .:.. :||:|::.||||.:|:||.:..:|..:|::|||||:|.:||||.| .|.|.||::  :..
Worm   104 DASY-STSVVVIHHNEALSTILRMINGIIEFTPKSLLKEIVLYEDASEEDHVLTKHLEKFAKIKG 167

  Fly   245 LPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPII 309
            |..|..:.|:|.|.|||||::..:...:||||.|:|:|||..|.||||||..|.::.:::|.|::
Worm   168 LEDKLIIKRSEYRQGLIRAKVHASRLATGEVIVFMDSHCEVAERWLEPLLQPIKEDPKSIVLPVV 232

  Fly   310 DVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYF 374
            |:|:..:|:| :.|.....||:|...|:|..:|........|: ..|..:|.|.|||.::.|:||
Worm   233 DLINPVSFDY-SPSMVAKSGFDWGFTFKWIYLPWEYFETPENN-VKPFNSPAMPGGLLAMRKEYF 295

  Fly   375 YEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTF-PGGTTEIVNHNNA 438
            .|:|.||.||:|||.||:|:|.:.|:|||.:.:|||||||||||...|||. ||..|.:  :|..
Worm   296 VELGEYDMGMEIWGSENIELSLKAWLCGGRVVVAPCSRVGHVFRMRRPYTSKPGMDTAL--YNAV 358

  Fly   439 RLVEVWLDDWKEFYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPE 492
            |:.:.||.:::..:::..|...|...||:::...::||||||..:|::||||||
Worm   359 RVAKTWLGEYESKFFAVKPRGAKMVFGDLTEPMQVKDRLKCKDMKWFIENVYPE 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	127/303 (42%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527
gly-8	NP_001366981.1	pp-GalNAc-T	110..410	CDD:133004	127/303 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820