DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant5 and gly-9

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001022876.1	Gene:	gly-9 / 176557	WormBaseID:	WBGene00012934	Length:	579	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	210/512 - (41%)
Similarity:	300/512 - (58%)	Gaps:	18/512 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 PSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCR--RKHY 182
            |:....:..|||.||||.:.....:|.:...|:...|:.|||.|||:|.:.|.|.:.|:  :..|
Worm    66 PNYTAPREGPGEKGKPVVLTGKDAELGQADMKKWFMNVHASDKISLDRDVPDPRIQACKDIKYDY 130

  Fly   183 ASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPV 247
            |: ||.||::|:|.:||||.|||||.|||||||..||:|:||:||.|:|..|.:.|:|::.:...
Worm   131 AA-LPKTSVIIIFTDEAWTPLLRTVHSVINRSPPELLQEVILLDDNSKRQELQEPLDEHIKRFGG 194

  Fly   248 KTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVI 312
            |..::|...|.|||||:|.||....|::|.|||:|||...|||||::.||...|..:|||:||.|
Worm   195 KVRLIRKHVRHGLIRAKLAGAREAVGDIIVFLDSHCEANHGWLEPIVQRISDERTAIVCPMIDSI 259

  Fly   313 SDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEI 377
            ||.|..|......:.|||:|.|:|.|..:...|..||... |..:|:|||||||.:.:::||:|:
Worm   260 SDNTLAYHGDWSLSTGGFSWALHFTWEGLSEEEQKRRTKP-TDYIRSPTMAGGLLAANREYFFEV 323

  Fly   378 GSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPG--GTTEIVNHNNARL 440
            |.|||.||||||||||:|||.|||||.:|..|||.|||:||...||...|  ...::...|:.||
Worm   324 GGYDEEMDIWGGENLEISFRAWMCGGSIEFIPCSHVGHIFRAGHPYNMTGRNNNKDVHGTNSKRL 388

  Fly   441 VEVWLDDWKEFYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYP-ESLMPLDYYYLGE 504
            .|||:||:|..||......|....||::.|..||.||.||.|:|:|:|:.. :.:|..|....|.
Worm   389 AEVWMDDYKRLYYMHREDLRTKDVGDLTARHELRKRLNCKPFKWFLDNIAKGKFIMDEDVVAYGA 453

  Fly   505 IRN--AETETCLDTMGR--KYNEKVGISYCHGLGGN-QVFAYTKRQQIMSDDLCLDASSSNGPVN 564
            :..  :.|..|.||:.|  |.::.:|:.:|.|.|.: |:.:.:|...:..::.|  ||..||.:.
Worm   454 LHTVVSGTRMCTDTLQRDEKMSQLLGVFHCQGKGSSPQLMSLSKEGNLRRENTC--ASEENGNIR 516

  Fly   565 MVRCHNMGG-NQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPC-SYGKGQQW 619
            |..|..... |:.|.|  |.|.||:..:|:|:..|.....:..::..| ...:.|:|
Worm   517 MKTCSKKAQFNERWAY--ENKMIRNLKSGKCMSTANLKPGDNAIVVECDEKDEHQKW 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	149/301 (50%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	32/122 (26%)
gly-9	NP_001022876.1	pp-GalNAc-T	137..438	CDD:133004	149/301 (50%)
		Ricin_B_lectin	450..571	CDD:279046	32/124 (26%)
		RICIN	458..573	CDD:238092	32/118 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920