Protein Alignment Pgant5 and GALNT15

DIOPT Version :9

• Sequence 1: NP_001036338.1
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_473451.3
• Gene: GALNT15 / 117248
• HGNCID: 21531
• Length: 639
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 196/532 - (36%)
• Similarity: 286/532 - (53%)
• Gaps: 47/532 - (8%)

  Fly   124 EAKGKPGEMGKPVKIP-------------ADMKDLMKEKFKENQFNL-------LASDMISLNRS 168
            :::|:.|...:.:|.|             ||....:.|:.:...|:|       ..|..|.|.|:
Human   108 QSQGRRGGSYRLIKQPRRQDKEAPKRDWGADEDGEVSEEEELTPFSLDPRGLQEALSARIPLQRA 172

  Fly   169 LTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDF 233
            |.:|||..|.::|....|||.|:::.||:|||:||||||.|:::..|||.|||||||||.|::..
Human   173 LPEVRHPLCLQQHPQDSLPTASVILCFHDEAWSTLLRTVHSILDTVPRAFLKEIILVDDLSQQGQ 237

  Fly   234 LGKQLEEYVAKLP-VKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARI 297
            |...|.||||:|. ||  :||:.||.|.||||:|||...:|:|:.|:||||||..|||||||:||
Human   238 LKSALSEYVARLEGVK--LLRSNKRLGAIRARMLGATRATGDVLVFMDAHCECHPGWLEPLLSRI 300

  Fly   298 VQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTM 362
            ..:|..||.|:||||..:||:|..:.|...|..:|||:|.|..:| ..:.:......:|:|:|.:
Human   301 AGDRSRVVSPVIDVIDWKTFQYYPSKDLQRGVLDWKLDFHWEPLP-EHVRKALQSPISPIRSPVV 364

  Fly   363 AGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPG 427
            .|.:.::|:.||...|:||..|.:.||||||:||:.|:|||.:||.|||||||:::....::  .
Human   365 PGEVVAMDRHYFQNTGAYDSLMSLRGGENLELSFKAWLCGGSVEILPCSRVGHIYQNQDSHS--P 427

  Fly   428 GTTEIVNHNNARLVEVWLDDWKEFYYSFYPGA---RKASAGDVSDRKALRDRLKCKSFRWYLENV 489
            ...|....|..|:.|.||..:||.:|...|.|   .||...|..:|..|:.||.|::|.|:|.||
Human   428 LDQEATLRNRVRIAETWLGSFKETFYKHSPEAFSLSKAEKPDCMERLQLQRRLGCRTFHWFLANV 492

  Fly   490 YPESLMPLD--YYYLGEIRNAETETCLDTMGRKYNEKVG----ISYCHGLGGNQVFAYTKRQQI- 547
            ||| |.|.:  ..:.|::.|.....|.|....  .:.:|    ::.|......|...:|.|::|
Human   493 YPE-LYPSEPRPSFSGKLHNTGLGLCADCQAE--GDILGCPMVLAPCSDSRQQQYLQHTSRKEIH 554

  Fly   548 --MSDDLCLDASSSNGPVNMVRCHNMG---GNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPL 607
              ....||.......  |.:..|...|   ..|.|.:. |...|.|..:|:|::...:::.....
Human   555 FGSPQHLCFAVRQEQ--VILQNCTEEGLAIHQQHWDFQ-ENGMIVHILSGKCMEAVVQENNKDLY 616

  Fly   608 LRPCSYGKGQQW 619
            ||||.....|||
Human   617 LRPCDGKARQQW 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	139/303 (46%)
		Ricin_B_lectin	503..619	CDD:395527	27/125 (22%)
GALNT15	NP_473451.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..155		8/46 (17%)
		Catalytic subdomain A	190..299		66/110 (60%)
		Glyco_tranf_2_3	191..447	CDD:290369	124/260 (48%)
		pp-GalNAc-T	194..493	CDD:133004	139/303 (46%)
		Catalytic subdomain B	358..420		32/61 (52%)
		Ricin_B_lectin	505..628	CDD:279046	27/127 (21%)
		RICIN	507..630	CDD:238092	29/127 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750