Protein Alignment Pgant5 and GALNT13

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001363332.1
• Gene: GALNT13 / 114805
• HGNCID: 23242
• Length: 571
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 346/606 - (57%)
• Similarity: 412/606 - (67%)
• Gaps: 61/606 - (10%)

  Fly    19 CRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEK 83
            |::||.|||:||:.|..|:..:|:|.     :|....|..: ||....::..||
Human     7 CKVVLATSLMWVLVDVFLLLYFSECN-----KCDDKKERSL-LPALRAVISRNQ----------- 54

  Fly    84 SLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKE 148
                         :|                              ||||||.|.||.|.::.|||
Human    55 -------------EG------------------------------PGEMGKAVLIPKDDQEKMKE 76

  Fly   149 KFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINR 213
            .||.|||||:|||:|:|||||.|||.|||:.|.|..:||.||:|||||||||:||||||:|||||
Human    77 LFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINR 141

  Fly   214 SPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITF 278
            ||..||.|:||||||||||||...||.||..|.|...::|.|:|||||||||.||....|:||||
Human   142 SPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKIIRMEERSGLIRARLRGAAASKGQVITF 206

  Fly   279 LDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPS 343
            ||||||||.||||||||||.::|:||||||||||||:||||:..||.|:||||||||||||.||.
Human   207 LDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQ 271

  Fly   344 REMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEII 408
            |||.||..|||.|:|||||||||||||::||.|||:||.|||||||||||||||||||||.|||:
Human   272 REMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIV 336

  Fly   409 PCSHVGHVFRDKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKAL 473
            .|||||||||..:|||||||...::..|..|:||||:||::||:|.:|.|..|...||||.||.|
Human   337 TCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTL 401

  Fly   474 RDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQV 538
            |:.||||.|.|||||:||:|.:|..||.||||||.||..|||.||||.||||||..|||:|||||
Human   402 RENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQV 466

  Fly   539 FAYTKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQ-RATRDD 602
            |:||..::|.:||||||.|..||||.|::||:|.|||.|.||||...:.|..|..||. ....|.
Human   467 FSYTADKEIRTDDLCLDVSRLNGPVIMLKCHHMRGNQLWEYDAETHTLLHIITQSCLSVNKVADG 531

  Fly   603 ANTPLLRPCSYGKGQQWLMES 623
            :..|.:..|:....|:||:.:
Human   532 SQHPTVETCNDSTLQKWLLRN 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	215/299 (72%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	68/126 (54%)
GALNT13	NP_001363332.1	pp-GalNAc-T	118..418	CDD:133004	215/299 (72%)
		beta-trefoil_Ricin-like	425..552	CDD:483949	68/126 (54%)