Protein Alignment Pgant5 and Galnt7

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_653332.3
• Gene: Galnt7 / 108150
• MGIID: 1349449
• Length: 657
• Species: Mus musculus
• Alignment Length: 603
• Identity: 231/603 - (38%)
• Similarity: 328/603 - (54%)
• Gaps: 49/603 - (8%)

  Fly    49 WRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVL 113
            |......|.|:|....:....:.|         |:...|:|...::..|.......:.||...||
Mouse    72 WPHVEGVEVDLESIRRKNKAKNEQ---------ERHAGGDSQRDVMQRQYLTFKPQTFTYRDPVL 127

  Fly   114 KKWFLA------PSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDV 172
            :...|.      |......|.|||..||:.:..:.|..::...||..||::|||||||:||:.|:
Mouse   128 RPGVLGNFEPKEPEPHGVVGGPGEKAKPLVLGPEYKQAVQASIKEFGFNMVASDMISLDRSVNDL 192

  Fly   173 RHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQ 237
            |.|.|:..||...|.|:|:|||||||.|:||:|||.|||.|:||..|.||:|:||.|.::.|.::
Mouse   193 RQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEK 257

  Fly   238 LEEYVAKL---PVKTFVLRTEKRSGLIRARLLGAEHVS-GEVITFLDAHCECTEGWLEPLLARIV 298
            |:||: ||   .||.|  |.|:|.|||:||.:||:... |:|:.:||||||....|..||:|.|.
Mouse   258 LDEYI-KLWNGLVKVF--RNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPIS 319

  Fly   299 QNRRTVVCPIIDVISDETFEYITASDSTWGGF---NWKLNFRWYRVP--SREMARRNNDRTAPLR 358
            ::|.....|||||||..|:|.|........|:   .|..:..|.|||  ||| .|....:|.|.|
Mouse   320 KDRTICTVPIIDVISGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTSRE-KRLRKTKTEPYR 383

  Fly   359 TPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFR----- 418
            :|.||||||:|:||:|:|:|.||.|:.||||||.|:|::||||||.|..:|||.|||::|
Mouse   384 SPAMAGGLFAIEKDFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQ 448

  Fly   419 DKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFR 483
            ...|..:.|  :...|.|..||.|||.||::|::|:....::....||:|:.|..|:...||||:
Mouse   449 GNPPPLYVG--SSPTLKNYVRVVEVWWDEYKDYFYASRPESKALPYGDISELKKFREDHNCKSFK 511

  Fly   484 WYLENV-------YPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQVFAY 541
            |::|.:       ||  |.|.:..: ||||..||..|:|:||:.....|.:..||.:||||:|..
Mouse   512 WFMEEIAYDITAHYP--LPPRNVEW-GEIRGLETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRI 573

  Fly   542 TKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTP 606
            .:..|:|..|.||........|.:..| |:...:||.|........|..:|:||.|:  :..:..
Mouse   574 NEANQLMQYDQCLTKGPDGSKVMITHC-NLNEFKEWQYFKSLHRFTHITSGKCLDRS--EVLHQV 635

  Fly   607 LLRPCSYGK-GQQWLMES 623
            .:..|...| .|:|.|.:
Mouse   636 FISTCDSSKMTQKWEMNN 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	145/320 (45%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	39/126 (31%)
Galnt7	NP_653332.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..105		5/30 (17%)
		Catalytic subdomain A	206..317		59/113 (52%)
		pp-GalNAc-T	210..518	CDD:133004	145/313 (46%)
		Catalytic subdomain B	381..443		39/61 (64%)
		beta-trefoil_Ricin_GALNT7	530..653	CDD:467315	39/126 (31%)