Protein Alignment Pgant5 and galnt6.3

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_004911960.1
• Gene: galnt6.3 / 100498043
• XenbaseID: XB-GENE-22063205
• Length: 622
• Species: Xenopus tropicalis
• Alignment Length: 649
• Identity: 259/649 - (39%)
• Similarity: 358/649 - (55%)
• Gaps: 97/649 - (14%)

  Fly    24 LTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGE 88
            :..:|:|||.|::.....:....|.|           :.|.  :|..:|::|
 Frog    15 MVGIVFVIFVFIMHKDVGNGAKDDPW-----------IKNI--VVRKDQMLD------------- 53

  Fly    89 SGGALIMGQGFASGGISMTYPSVVLKKWFLAP-----SVQEAK---------------------- 126
                  |.:| |...:..:.|    |...:||     .|:|.|
 Frog    54 ------MMRG-AMNNLKDSIP----KLQIMAPVQEEGPVEEKKLCLPGYYTPAELKPFMERPPQD 107

  Fly   127 -GKPGEMGKPVKIPADMKDLMKEK---FKENQFNLLASDMISLNRSL-TDVRHEGCRRKHY--AS 184
             ..||..||..|.....::..|||   |.::.||..|||.|||:|:| .|.|...|..:.:  ..
 Frog   108 PNSPGADGKGFKKDTWTEEETKEKEKGFDKHCFNAFASDRISLHRALGPDTRPPVCIEQKFKRCP 172

  Fly   185 KLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKT 249
            .|||||::||||||||:||||||:||:..||..|||||||||||||.::|.::|::||..|.: .
 Frog   173 SLPTTSVIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKEKLDDYVKALQI-V 236

  Fly   250 FVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISD 314
            .:.|.::|.|||.||||||...:|||:|||||||||..|||||||:||.::...||.|.|..|..
 Frog   237 KIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRIAEDHTAVVSPDITTIDL 301

  Fly   315 ETFEYIT----ASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFY 375
            .:||:..    ....:.|.|:|.|.|.|..:|:.|..|| .|.|.|:::||.|||||||.|.||.
 Frog   302 NSFEFAKPVQYGKTHSRGNFDWSLTFGWEAIPAAEKERR-KDETYPIKSPTFAGGLFSISKAYFE 365

  Fly   376 EIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARV 440
            .||||||.|:||||||:|||||:|||||.|||||||.||||||.|||:|||.| .:::..|..|:
 Frog   366 HIGSYDEEMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKG-TQVISRNQVRL 429

  Fly   441 AEVWLDEWRDFYYSMSTGA----RKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMP-LDYY 500
            ||||:|:::..||..:..|    |:.|.||:|.|..|:..|:||:|.|||||:|||..:| .|..
 Frog   430 AEVWMDDYKLIYYRRNEQAAKMVREKSFGDISKRLKLKADLQCKNFTWYLENIYPEMFVPDRDPT 494

  Fly   501 YLGEIRNAETETCLDTMGRKYNEKVGISY-CHGLGGNQVFAYTKRQQI---MSDDLCLDASSSNG 561
            |.|.::|..::.|||.....:..|..|.| |||:||||.|.|:..:::   ::..|||.:....|
 Frog   495 YYGAVKNEGSQNCLDVGENNHGGKPLIMYPCHGMGGNQYFEYSTHKELRHNIAKQLCLRSKYGPG 559

  Fly   562 PVNMVRCHNMG------GNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPCSYGKGQQW 619
            ||.:..|...|      ||:||.. .:::.:::..:..|| .|..::.:|....|...  .|:|
 Frog   560 PVELGECQYKGKKTTVPGNEEWEL-TKDRLLKNVGSNMCL-TARGENPSTAECNPSDI--HQRW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	170/307 (55%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	38/133 (29%)
galnt6.3	XP_004911960.1	pp-GalNAc-T	178..483	CDD:133004	170/307 (55%)
		beta-trefoil_Ricin_GALNT6	493..622	CDD:467348	37/131 (28%)