DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt9

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_002931923.1	Gene:	galnt9 / 100490061	XenbaseID:	XB-GENE-948907	Length:	604	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	194/532 - (36%)
Similarity:	291/532 - (54%)	Gaps:	52/532 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 PGEMGKPVKIPADMKDLMKE---KFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTS 190
            ||.:|:. .:.|.::|...|   |::|..:|...||.|||:||:.|.|.:.|::..|...||..:
Frog    92 PGGLGQG-GMAATLRDDSHESETKYEEYGYNAQLSDRISLDRSIPDYRPKKCKQMTYPDDLPQIA 155

  Fly   191 IVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAK-LPVKTFVLRT 254
            :|.:|.|||.:.:||:|.||:|.:|..||||||||||.|:...|...|::||.| .|....::|.
Frog   156 VVFIFVNEALSVILRSVHSVVNHTPSYLLKEIILVDDNSDNVELKFNLDQYVNKRYPGLVKIVRN 220

  Fly   255 EKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFE- 318
            .:|.||||||:.|.:..|..::.|.|||.|...||.||::.||.::||.::.|.||.|...:||
Frog   221 TRREGLIRARIQGWKAASAPIVGFFDAHVEFNTGWAEPVITRIKEDRRRIILPAIDNIKYNSFEV 285

  Fly   319 --YITASDSTWGGFNWKLNFRW--YRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGS 379
              |..|:.    |:||.|   |  |..|.::...: .|.:||:|||.|.|..|.:|:.||.:||.
Frog   286 QQYANAAH----GYNWGL---WCMYITPPQDWLEK-GDESAPIRTPAMIGCSFVVDRAYFGDIGL 342

  Fly   380 YDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVW 444
            .|.||:::||||:|:..|||.|||.:|:.|||||.|:.|...||.  .........|..|..|||
Frog   343 LDPGMEVYGGENIELGMRVWQCGGSMEVLPCSRVAHIERTKKPYN--NDIDYYAKRNALRAAEVW 405

  Fly   445 LDDWKEFYYSFY------PGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLG 503
            :|::|...|..:      ||   ...||||:|.|||.:|:|:||:|||||||||..:..:....|
Frog   406 MDEFKSHVYMAWNIPMTNPG---VDFGDVSERVALRQKLQCRSFKWYLENVYPEMRVYNNTITYG 467

  Fly   504 EIRNAE-TETCLDTMGRKYNEKVGISYCHGLGGNQVFAYTKR----------QQIMSDDLCLDAS 557
            |:||:: |..||| .|.:.:.|..:..|||: .:|:..|:..          ...:.|..||...
Frog   468 ELRNSKATGYCLD-QGSEDDNKAILYPCHGM-SSQLVRYSSEGLLQLGPLGSTSFLPDTKCLIDD 530

  Fly   558 SSNGPVNMVRCHNMGGNQEWVYD-AEEKWIRHTNTGQCLQRATRDDANTPL---LRPCSYGKGQQ 618
            .......:.:|.::..:.:.::| .:...|.:.:||:||:.....|||..|   ::.||   ||:
Frog   531 GKGRTPTLKKCDDVPRSPQKLWDFTQSSPIVNRDTGRCLEVEMSKDANFGLRLVVQRCS---GQK 592

  Fly   619 WLMESKFKWQAH 630
            |::.:   |..|
Frog   593 WIIRN---WIKH 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	132/311 (42%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	33/130 (25%)
galnt9	XP_002931923.1	pp-GalNAc-T	156..454	CDD:133004	132/310 (43%)
galnt9	XP_002931923.1	Ricin_B_lectin	465..593	CDD:366226	33/132 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910