Protein Alignment Pgant5 and galnt3

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_002936794.2
• Gene: galnt3 / 100488466
• XenbaseID: XB-GENE-954414
• Length: 625
• Species: Xenopus tropicalis
• Alignment Length: 546
• Identity: 248/546 - (45%)
• Similarity: 333/546 - (60%)
• Gaps: 52/546 - (9%)

  Fly   108 YPSVVLKKWFLAPSVQEAKGKPGEMGKPVK----IPADMKDLMKEK-FKENQFNLLASDMISLNR 167
            |.:..||. ||....|:... ||..|||.|    .|.:.::  ||: .|::.||..|:|.|||:|
 Frog    94 YTAAELKP-FLERPPQDPHA-PGAAGKPFKEEKLTPEEQEE--KERGEKKHCFNAFATDRISLHR 154

  Fly   168 SL-TDVRHEGCRRKHY--ASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDAS 229
            .| .|.|...|..:.:  ...||||||:||||||||:||||||:||::.||..||||||||||||
 Frog   155 DLGPDTRPPECIEQKFKRCPPLPTTSIIIVFHNEAWSTLLRTVYSVMHTSPAILLKEIILVDDAS 219

  Fly   230 ERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLL 294
            ..::|..:|:|||.:|.: ..|:|.::|.|||.||||||...:|:.:|||||||||..|||||||
 Frog   220 VDEYLKDELDEYVKQLQI-VKVVRQKERKGLITARLLGASVATGDTLTFLDAHCECYYGWLEPLL 283

  Fly   295 ARIVQNRRTVVCPIIDVISDETFEYITAS----DSTWGGFNWKLNFRWYRVPSREMARRNNDRTA 355
            |||.:|..:||.|.|..|...||::...|    :...|.|:|.|:|.|..:||.|..|| .|.|.
 Frog   284 ARIAENYTSVVSPDITGIDLNTFQFSNPSPYGNNHNRGNFDWTLSFGWESLPSSEKTRR-KDETY 347

  Fly   356 PLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDK 420
            |::|||.|||||||.|.||..||||||.|:||||||:|||||:|||||.|||:|||.||||||.|
 Frog   348 PIKTPTFAGGLFSISKAYFEHIGSYDEQMEIWGGENIEMSFRVWQCGGQLEILPCSVVGHVFRSK 412

  Fly   421 SPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGA----RKASAGDVSDRKALRDRLKCKS 481
            ||:|||.| .::::.|..|:||||:|:.::.:|..:..|    :....||:|.|..||.||:||:
 Frog   413 SPHTFPKG-TQVIVRNQVRLAEVWMDDLKEIFYRRNREAANIVKSKEYGDLSKRLDLRHRLQCKN 476

  Fly   482 FRWYLENVYPESLMPLDYYYL-GEIRNAETETCLDTMGRKYNEKVGISY-CHGLGGNQVFAYTKR 544
            |.|||.|:|||..:|..:..: |:::|...:.|||..|..:.:|..|.| ||||||||.|.||.:
 Frog   477 FTWYLNNIYPEMYVPERHPLIHGDLKNVGRDLCLDVGGENHGDKPLIMYSCHGLGGNQYFEYTSK 541

  Fly   545 QQI---MSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQR--------- 597
            .:|   :..:|||..|.|:  :.:..|:..|  ::.....||:|.        |||
 Frog   542 HEIRHNIQKELCLRPSHSS--LVIKPCNYRG--RDTAPLPEERWE--------LQREQLLFNPSY 594

  Fly   598 ---ATRDDANTPLLRPCSYGKGQQWL 620
               .:.:.||..|::.......|||:
 Frog   595 NLCVSSEGANPTLVQCNPADPFQQWI 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	172/307 (56%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	40/141 (28%)
galnt3	XP_002936794.2	pp-GalNAc-T	180..485	CDD:133004	172/307 (56%)
		beta-trefoil_Ricin-like	495..622	CDD:483949	40/138 (29%)