Protein Alignment Pgant5 and galnt6.2

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_031753046.1
• Gene: galnt6.2 / 100486937
• XenbaseID: XB-GENE-1000674
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 641
• Identity: 265/641 - (41%)
• Similarity: 362/641 - (56%)
• Gaps: 96/641 - (14%)

  Fly    24 LTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGE 88
            :..:|:|||.|::.....:....|.|           :.|.  :|..:|:::
 Frog    15 MVGMVFVIFVFIMHKDIGNGAKDDPW-----------IKNI--VVRKDQMIN------------- 53

  Fly    89 SGGALIMGQGFASGGISMTYPSVVLKKWFLAP-----SVQEAKG------KPGE----MGKPVKI 138
                  |.:| |...:..:.|    |...:||     .|:|.|.      .|.|    |.:|.:.
 Frog    54 ------MMRG-AMKNLKDSIP----KLQIMAPVQEVRPVEEKKSCLPGYYTPAELKPFMERPPQD 107

  Fly   139 P----ADMKDLM-----------KEK-FKENQFNLLASDMISLNRSL-TDVRHEGCRRKHY--AS 184
            |    ||.|..:           ||| |.::.||..|||.|||:|:| .|.|...|..:.:  ..
 Frog   108 PNSPGADGKGFIKNIWTEEEVEEKEKGFDKHCFNAFASDRISLHRALGPDTRPLECIEQKFKRCP 172

  Fly   185 KLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKT 249
            .||||||:||||||||:||||||:||:..||..|||||||||||||.::|.::|::||..|.: .
 Frog   173 SLPTTSIIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKEKLDDYVKALQI-V 236

  Fly   250 FVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISD 314
            .:.|.::|.|||.||||||...:|||:|||||||||..|||||||:|:.::...||.|.|..|:.
 Frog   237 KIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRVAEDHTAVVSPDITAINY 301

  Fly   315 ETFEY----ITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFY 375
            .|||:    .....::.|.|:|.|.|.|..:|:.:..:| .|.|.|::|||.|||||||.|.||.
 Frog   302 NTFEFGKPVQQGKMNSRGNFDWSLAFNWEAIPAADEKQR-KDETYPIKTPTFAGGLFSISKAYFE 365

  Fly   376 EIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARV 440
            .||||||.|:||||||:|||||:|||||.|||||||.||||||.|||:|||.| .:::|.|..|:
 Frog   366 HIGSYDEEMEIWGGENVEMSFRVWQCGGKLEIIPCSVVGHVFRTKSPHTFPKG-TQVILRNQVRL 429

  Fly   441 AEVWLDEWRDFYYSMSTGARK----ASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMP-LDYY 500
            ||||:|:::..||..:..|.|    .|.||:|.|..|:..|:||:|.|||||:|||..:| .|..
 Frog   430 AEVWMDDYKVLYYRRNEQAAKIAKEKSFGDISKRLKLKADLQCKNFTWYLENIYPEMFVPDRDPT 494

  Fly   501 YLGEIRNAETETCLDT-MGRKYNEKVGISY-CHGLGGNQVFAYTKRQQI---MSDDLCLDASSSN 560
            |.|.|:|..|:.|:|. ....|..::.|.| |||:||||.|.|:..:::   :...|||.:....
 Frog   495 YYGAIKNEGTQNCIDVGENNNYGSQLPIMYPCHGMGGNQYFEYSTHKELRHNLKTQLCLCSKYEP 559

  Fly   561 GPVNMVRCHNMG------GNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRP 610
            |||.:|.|...|      ||:||.: .:::.||:..:..|| .|..|..:|....|
 Frog   560 GPVKLVDCQYKGQNTTVPGNEEWEF-TKDRLIRNVGSNMCL-TAQGDHPSTAECNP 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	171/307 (56%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	41/125 (33%)
galnt6.2	XP_031753046.1	pp-GalNAc-T	178..483	CDD:133004	171/307 (56%)
		beta-trefoil_Ricin-like	493..623	CDD:483949	40/123 (33%)