DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt3

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_021334717.1	Gene:	galnt3 / 100331984	ZFINID:	ZDB-GENE-120313-1	Length:	625	Species:	Danio rerio

Alignment Length:	673	Identity:	278/673 - (41%)
Similarity:	363/673 - (53%)	Gaps:	108/673 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TFTRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVD 69
            ||.|::. |.|.:..::.:: :||:|.|.|::                            :|.|.
Zfish     2 TFIRRLL-RRRLHPLKLAIV-ALVFVTFLFLM----------------------------QREVV 36

  Fly    70 DNQLVDDNEIN--TEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAP-SVQEAKGK--- 128
            .....|:..:.  .||. ||..|  ::||   |........|.:.:|    || ..||::|.
Zfish    37 SQSPQDEPWLRGIVEKR-DGVLG--MVMG---AVNNFRDAMPKMQIK----APVRQQESQGSSAC 91

  Fly   129 -----------------------PGEMGKPVKI----PADMKDLMKEKFKENQ-FNLLASDMISL 165
                                   ||..||....    .::.|:  ||:.:|.. |||.|||.|||
Zfish    92 LSGYYTPAELKPVLERPPQNPSAPGASGKAFHTDNLSSSEQKE--KERGEEKHCFNLYASDRISL 154

  Fly   166 NRSL-TDVRHEGCRRKHY--ASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDD 227
            :|.| .|.|...|..:.:  ...|||||::||||||||:||||||:||::.||...|||||||||
Zfish   155 SRDLGPDTRPPECIEQTFRRCPPLPTTSVIIVFHNEAWSTLLRTVYSVLHTSPALFLKEIILVDD 219

  Fly   228 ASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEP 292
            ||..:.|..:|:|::.:|.: ..|:|..:|.|||.||||||...:|:.:|||||||||..|||||
Zfish   220 ASVDEHLKDKLDEFLKQLHI-VRVVRQHERKGLITARLLGASVATGDTLTFLDAHCECFHGWLEP 283

  Fly   293 LLARIVQNRRTVVCPIIDVISDETFEYITAS----DSTWGGFNWKLNFRWYRVPSREMARRNNDR 353
            |||||.:|...||.|.|..|...|||::..|    ....|.|:|.|:|.|..:|..| .||..|.
Zfish   284 LLARIAENSSAVVSPDITTIDLNTFEFMKPSPYGQHHNRGNFDWGLSFGWETLPDHE-RRRRKDE 347

  Fly   354 TAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFR 418
            |.|::|||.|||||||.:||||.||||||.|:||||||:|||||||.|||.|||.|||.||||||
Zfish   348 TYPIKTPTFAGGLFSISRDYFYHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIIPCSVVGHVFR 412

  Fly   419 KSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYY----SFYPGARKASAGDVSDRKALRDRLKC 479
            ..:|:|||.| |:::..|..||.|||:||:||.:|    .....|::.|.||||.|..||:||:|
Zfish   413 TKSPHTFPKG-TQVIARNQVRLAEVWMDDYKEIFYRRNQQAAQIAKEHSFGDVSRRVDLRERLQC 476

  Fly   480 KSFRWYLENVYPESLMP-LDYYYLGEIRNAETETCLDTMGRKYNEKVGISY-CHGLGGNQVFAYT 542
            |||.|||:|||||..|| |:....|.|||...|.|||........|..|.| |||:||||.|.|:
Zfish   477 KSFSWYLKNVYPEVFMPDLNPLQFGAIRNMGKEACLDVGESNEGGKPLIMYPCHGMGGNQYFEYS 541

  Fly   543 KRQQI---MSDDLCLDASSSNGPVNMVRCHNMGGN------QEWVYDAEEKWIRHTNTGQCLQRA 598
            ...:|   :..:|||| .:....|.:..|...|.|      |:|.. .|::...:..:.|||...
Zfish   542 THHEIRHNIQKELCLD-GTDGAMVRLEECQYKGHNTITSPQQKWEL-REDQLFYNKASKQCLSAR 604

  Fly   599 TRDDANTPLLRPCS-YGKGQQWL 620
            ..:    |.|.||: ..|.|.||
Zfish   605 PEN----PSLVPCNPDDKYQLWL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	174/307 (57%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	41/126 (33%)
galnt3	XP_021334717.1	pp-GalNAc-T	182..487	CDD:133004	174/307 (57%)
galnt3	XP_021334717.1	Ricin_B_lectin	500..622	CDD:306998	41/127 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587007
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950