Protein Alignment Pgant5 and galnt3

DIOPT Version :10

• Sequence 1: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_021334717.1
• Gene: galnt3 / 100331984
• ZFINID: ZDB-GENE-120313-1
• Length: 625
• Species: Danio rerio
• Alignment Length: 673
• Identity: 277/673 - (41%)
• Similarity: 367/673 - (54%)
• Gaps: 108/673 - (16%)

  Fly     5 TFTRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVD 69
            ||.|::. |.|.:..::.:: :||:|.|.|::                            :|.|.
Zfish     2 TFIRRLL-RRRLHPLKLAIV-ALVFVTFLFLM----------------------------QREVV 36

  Fly    70 DNQLVDDNEIN--TEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAP-SVQEAKGK--- 128
            .....|:..:.  .||. ||..|  ::||   |........|.:.:|    || ..||::|.
Zfish    37 SQSPQDEPWLRGIVEKR-DGVLG--MVMG---AVNNFRDAMPKMQIK----APVRQQESQGSSAC 91

  Fly   129 -----------------------PGEMGKPVKI----PADMKDLMKEKFKENQ-FNLLASDMISL 165
                                   ||..||....    .::.|:  ||:.:|.. |||.|||.|||
Zfish    92 LSGYYTPAELKPVLERPPQNPSAPGASGKAFHTDNLSSSEQKE--KERGEEKHCFNLYASDRISL 154

  Fly   166 NRSL-TDVRHEGCRRKHY--ASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDD 227
            :|.| .|.|...|..:.:  ...|||||::||||||||:||||||:||::.||...|||||||||
Zfish   155 SRDLGPDTRPPECIEQTFRRCPPLPTTSVIIVFHNEAWSTLLRTVYSVLHTSPALFLKEIILVDD 219

  Fly   228 ASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEP 292
            ||..:.|..:|:|::.:|.: ..|:|..:|.|||.||||||...:|:.:|||||||||..|||||
Zfish   220 ASVDEHLKDKLDEFLKQLHI-VRVVRQHERKGLITARLLGASVATGDTLTFLDAHCECFHGWLEP 283

  Fly   293 LLARIVQNRRTVVCPIIDVISDETFEYITAS----DSTWGGFNWKLNFRWYRVPSREMARRNNDR 353
            |||||.:|...||.|.|..|...|||::..|    ....|.|:|.|:|.|..:|..| .||..|.
Zfish   284 LLARIAENSSAVVSPDITTIDLNTFEFMKPSPYGQHHNRGNFDWGLSFGWETLPDHE-RRRRKDE 347

  Fly   354 TAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFR 418
            |.|::|||.|||||||.:||||.||||||.|:||||||:|||||:|||||.|||||||.||||||
Zfish   348 TYPIKTPTFAGGLFSISRDYFYHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIIPCSVVGHVFR 412

  Fly   419 DKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTG----ARKASAGDVSDRKALRDRLKC 479
            .|||:|||.| .:::..|..|:||||:|::::.:|..:..    |::.|.||||.|..||:||:|
Zfish   413 TKSPHTFPKG-TQVIARNQVRLAEVWMDDYKEIFYRRNQQAAQIAKEHSFGDVSRRVDLRERLQC 476

  Fly   480 KSFRWYLENVYPESLMP-LDYYYLGEIRNAETETCLDTMGRKYNEKVGISY-CHGLGGNQVFAYT 542
            |||.|||:|||||..|| |:....|.|||...|.|||........|..|.| |||:||||.|.|:
Zfish   477 KSFSWYLKNVYPEVFMPDLNPLQFGAIRNMGKEACLDVGESNEGGKPLIMYPCHGMGGNQYFEYS 541

  Fly   543 KRQQI---MSDDLCLDASSSNGPVNMVRCHNMGGN------QEWVYDAEEKWIRHTNTGQCLQRA 598
            ...:|   :..:|||| .:....|.:..|...|.|      |:|.. .|::...:..:.|||...
Zfish   542 THHEIRHNIQKELCLD-GTDGAMVRLEECQYKGHNTITSPQQKWEL-REDQLFYNKASKQCLSAR 604

  Fly   599 TRDDANTPLLRPCS-YGKGQQWL 620
            ..:    |.|.||: ..|.|.||
Zfish   605 PEN----PSLVPCNPDDKYQLWL 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	173/307 (56%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	44/135 (33%)
galnt3	XP_021334717.1	pp-GalNAc-T	182..487	CDD:133004	173/307 (56%)
		beta-trefoil_Ricin_GALNT3	496..625	CDD:467346	43/134 (32%)