DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant5 and galnt18a

DIOPT Version :9

Sequence 1:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_009296148.3	Gene:	galnt18a / 100170813	ZFINID:	ZDB-GENE-080723-30	Length:	696	Species:	Danio rerio

Alignment Length:	522	Identity:	189/522 - (36%)
Similarity:	283/522 - (54%)	Gaps:	63/522 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 EMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVF 195
            |:|     |...|..:: ||:...:|...||.:||:|::.|:|.:|||...|.:.||..||:.:|
Zfish   194 ELG-----PESRKVALR-KFQYYGYNAYLSDRLSLDRAVPDLRPDGCRNISYPTGLPQVSIIFIF 252

  Fly   196 HNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYV--AKLPVKTF--VLRTEK 256
            .|||.:.:||:|.|||.|:|..||||||||||.|..:.| :.|:.:|  .....:.|  |:..||
Zfish   253 VNEALSVILRSVHSVIQRTPAHLLKEIILVDDHSNNELL-ENLQRFVDETNQQQRDFIKVVHHEK 316

  Fly   257 RSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYIT 321
            :.||||:|:.|....|..::...|||.|.:.||.||:|.||.::|..|:.|..|.|..:||| |.
Zfish   317 QEGLIRSRVSGWRAASAPIVALFDAHVEFSIGWAEPILHRIQEDRTRVISPSFDNIKYDTFE-IE 380

  Fly   322 ASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDI 386
            ....:..||:|:|..|:...|.....::|  :|||:|:|.:. |.|.:|::||.|||..||||::
Zfish   381 EYPLSAQGFDWELWCRYLNPPKSWWMQKN--QTAPIRSPALI-GCFVVDREYFEEIGLLDEGMEV 442

  Fly   387 WGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEF 451
            :||||:|:..|||:|||.:|:.||||:.|:.|...|||....|.  |..|..|:.|||:|::|..
Zfish   443 YGGENVELGIRVWLCGGSVEVIPCSRIAHIERAHKPYTEDLATH--VRRNALRVAEVWMDEFKSH 505

  Fly   452 YYSFYPGARKASA---GDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNA-ETET 512
            .|..:...::.|.   ||:.||||||:||:||.|.|:|.|:|.|....:|....|.:||: ..:.
Zfish   506 VYMAWNIPQQDSGIDIGDIRDRKALRERLRCKPFSWFLNNIYSEMRTYMDTIAYGVLRNSLRPDL 570

  Fly   513 CLDTMGRKYNEKVGISY-CHGLGGNQVFAYTKRQQIM----------SDDLCL-DASS------- 558
            |:| .|.. ::.:.|.| ||||....|: :|..||:.          .|:.|| |.:|
Zfish   571 CVD-QGPD-SDNIPILYICHGLTPQNVY-FTSSQQLHVGGLSPTIDDDDNKCLVDVNSRPRLLEC 632

  Fly   559 ---SNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCL---QRATRDDANTPLLRPCSYGKGQ 617
               ||..:.:......||:           |::..:.:||   :.|..|.....:|:.||   .|
Zfish   633 SYASNKHMKLSWLFTQGGS-----------IQNKKSKRCLELVESADVDHGYQLVLQKCS---SQ 683

  Fly   618 QW 619
            :|
Zfish   684 KW 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	131/306 (43%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	34/141 (24%)
galnt18a	XP_009296148.3	pp-GalNAc-T	247..547	CDD:133004	131/306 (43%)
galnt18a	XP_009296148.3	RICIN	560..687	CDD:238092	35/143 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587008
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840