Protein Alignment CG31650 and RCN3

DIOPT Version :10

• Sequence 1: NP_608899.1
• Gene: CG31650 / 326150
• FlyBaseID: FBgn0031673
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: XP_024307388.1
• Gene: RCN3 / 57333
• HGNCID: 21145
• Length: 365
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 121/387 - (31%)
• Similarity: 179/387 - (46%)
• Gaps: 79/387 - (20%)

  Fly     9 PLTLCAVALL--AAVG-PMPAHGAVANSHKHEKHLSKERVKDGIYAP-RDAHHHGEDGEHNVEFD 69
            |..|..:.||  .|.| |.|..|.......|:.            || .||.|  :|...|.::|
Human     5 PSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQA------------APLSDAPH--DDAHGNFQYD 55

  Fly    70 HEAIIGNTKEAQEFDSLSPDESKRRLLILIKMMDL--NKDEFIDRHELKAWILRSFKKLSEEEAA 132
            |||.:|. :.|:|||.|:|:||:.||..::..||.  :.|.::...||:|||..:.::...:..:
Human    56 HEAFLGR-EVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVS 119

  Fly   133 DRFEEIDQDADERITWKEYLQDTYA--MEDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTNKD 195
            ..::..|.|.|.|:.|:|....||.  ...|:|.    |.:..|..:||:.:|:..|..||.:.|
Human   120 AAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFH----DVEDAETYKKMLARDERRFRVADQDGD 180

  Fly   196 GVLTLEEFVLFQNPEEHPQM-------------------------------------LPILLEHT 223
            .:.|.||...|.:|||.|.|                                     .|.||:.|
Human   181 SMATREELTAFLHPEEFPHMRDIVIALPGAKFPREPLTLTPGVQPPPGARVIGPQPQCPFLLQET 245

  Fly   224 MQDKDADHDGKINFQEFVGDAAS----HHDKEWLITEKERFDKDHDSNGDGVLTGDEVLSWIVPS 284
            ::|.|.:.||.:..:|::.|..|    ..:..|:.||:::|....|.|.||.|.|.||..|::|.
Human   246 LEDLDRNKDGYVQVEEYIADLYSAEPGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPP 310

  Fly   285 NTAIAND----EVDHLFVSTDEDHDDRLSYLEILNNYDTFVGSEATDYGDHLQNINHLSDEL 342
                |.|    |.:||...:|.|.|.|||..|||.|::.||||:||:||:.|.. :|  |||
Human   311 ----AQDQPLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTR-HH--DEL 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31650	NP_608899.1	EFh_CREC_RCN2_like	58..322	CDD:320025	94/312 (30%)
		EF-hand motif	58..88	CDD:320025	12/29 (41%)
		EF-hand motif	94..123	CDD:320025	10/30 (33%)
		EF-hand motif	130..159	CDD:320025	8/30 (27%)
		EF-hand motif	182..211	CDD:320025	10/28 (36%)
		EF-hand motif	219..248	CDD:320025	10/32 (31%)
		EF-hand motif	256..285	CDD:320025	12/28 (43%)
		EF-hand motif	292..322	CDD:320025	14/29 (48%)
RCN3	XP_024307388.1	EFh_CREC_RCN3	44..348	CDD:320028	95/314 (30%)
		EF-hand motif	44..73	CDD:320028	13/31 (42%)
		EF-hand motif	79..110	CDD:320028	10/30 (33%)
		EF-hand motif	117..146	CDD:320028	8/28 (29%)
		EF-hand motif	167..196	CDD:320028	10/28 (36%)
		EF-hand motif	204..270	CDD:320028	11/65 (17%)
		EF-hand motif	282..311	CDD:320028	12/32 (38%)
		EF-hand motif	318..348	CDD:320028	14/29 (48%)