DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31650 and calua

DIOPT Version :9

Sequence 1:	NP_001162879.1	Gene:	CG31650 / 326150	FlyBaseID:	FBgn0031673	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001002151.2	Gene:	calua / 415241	ZFINID:	ZDB-GENE-040625-166	Length:	317	Species:	Danio rerio

Alignment Length:	341	Identity:	122/341 - (35%)
Similarity:	191/341 - (56%)	Gaps:	31/341 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LPLLPLTLCAVALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGEDGEHNVEFD 69
            :.:.||.:|....:          ..|.|...||   |:||...  ||..:..| :||. |.|:|
Zfish     3 MEIRPLLMCFALCV----------VYATSKPTEK---KDRVHHD--APLSSKEH-DDGT-NFEYD 50

  Fly    70 HEAIIGNTKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEEAADR 134
            |:|.:|. :||:.||.|:|:|||.||..:::.:|.::|.|:...||||||.::.||...:....:
Zfish    51 HDAFLGE-EEAKTFDDLTPEESKNRLGKIVEKIDADEDGFVTEAELKAWIKKAQKKYIYDNVERQ 114

  Fly   135 FEEIDQDADERITWKEYLQDTYAMEDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTNKDGVLT 199
            :::.|.:.|..|:|:||...||....:|.:.:    |.|..:| |:.:|:..|..||.|.|.:..
Zfish   115 WKDFDLNNDRMISWEEYKNVTYGTYLDDPEPD----DGYNYKQ-MMARDERRFKMADGNGDHIAD 174

  Fly   200 LEEFVLFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGDAASHHDK----EWLITEKERF 260
            .|||..|.:|||:..|..|::..||:|.|.:.||.|:.:|::||..:|.|:    ||:.||:|:|
Zfish   175 KEEFTAFLHPEEYEHMKDIVVLETMEDIDKNGDGFIDLEEYIGDMYNHEDEMDEPEWVATEREQF 239

  Fly   261 DKDHDSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDTFVGSEA 325
            .:..|.|.||.:..:|.:.||:|::...|..|..||...:|.:.|.:|:..||||.||.||||:|
Zfish   240 SEFRDKNKDGKMDREETMDWILPADYDHAEAEAKHLVYESDTNKDGKLTKEEILNKYDLFVGSQA 304

  Fly   326 TDYGDHLQNINHLSDE 341
            ||:|:.|  :.|  ||
Zfish   305 TDFGEAL--VRH--DE 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31650	NP_001162879.1	EF-hand_7	100..153	CDD:290234	17/52 (33%)
		EFh	100..153	CDD:298682	17/52 (33%)
		EF-hand_7	184..241	CDD:290234	22/56 (39%)
		EFh	184..241	CDD:298682	22/56 (39%)
		EFh	228..281	CDD:298682	20/56 (36%)
calua	NP_001002151.2	EF-hand_7	75..132	CDD:290234	17/56 (30%)
		EF-hand_7	159..216	CDD:290234	22/56 (39%)
		EFh	159..216	CDD:298682	22/56 (39%)
		EFh	200..260	CDD:238008	21/59 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4223
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820