DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31650 and calu

DIOPT Version :9

Sequence 1:	NP_001162879.1	Gene:	CG31650 / 326150	FlyBaseID:	FBgn0031673	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_998840.1	Gene:	calu / 407965	XenbaseID:	XB-GENE-1007422	Length:	315	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	115/344 - (33%)
Similarity:	186/344 - (54%)	Gaps:	47/344 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LTLCAVALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGE------DGEHNVEF 68
            |.||....:|.|...|.          ||   |:||          ||..:      |...|.::
Frog     6 LLLCLCLWVACVVSKPT----------EK---KDRV----------HHDPQLSEKVHDDAQNFDY 47

  Fly    69 DHEAIIGNTKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEEAAD 133
            ||:|.:| .:||:.||.|:|:|||.||..::..:|.:||.::..:||:.||:.:.|:...|:...
Frog    48 DHDAFLG-AEEAKTFDQLTPEESKERLGRIVGKIDADKDGYVTVNELRDWIIFAQKRWIYEDVER 111

  Fly   134 RFEEIDQDADERITWKEYLQDTYA--MEDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTNKDG 196
            :::..|.:.|..::|:||...||.  ::|.|      ..:|:..:|.|:: |:..|..||.:.|.
Frog   112 QWKGHDLNGDSMVSWEEYKNATYGYILDDPD------PDNSFNYKQMMVR-DERRFKMADQDGDL 169

  Fly   197 VLTLEEFVLFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGDAASH----HDKEWLITEK 257
            :.|.|||..|.:|||...|..|::..||:|.|.:.||.|:.:|::||..:|    ::.||:.||:
Frog   170 IATKEEFTAFLHPEEFDYMKDIVVLETMEDIDKNGDGLIDLEEYIGDMYNHDGDANEPEWVKTER 234

  Fly   258 ERFDKDHDSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDTFVG 322
            |:|.:..|.|.||.:..:|...||:||:...|..|..||...:|::.|.:|:..||::.||.|||
Frog   235 EQFVEFRDKNHDGKMDKEETKDWILPSDYDHAEAESRHLVYESDQNKDSKLTREEIVDKYDLFVG 299

  Fly   323 SEATDYGDHLQNINHLSDE 341
            |:|||:|:.|  :.|  ||
Frog   300 SQATDFGEAL--VRH--DE 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31650	NP_001162879.1	EF-hand_7	100..153	CDD:290234	14/52 (27%)
		EFh	100..153	CDD:298682	14/52 (27%)
		EF-hand_7	184..241	CDD:290234	22/56 (39%)
		EFh	184..241	CDD:298682	22/56 (39%)
		EFh	228..281	CDD:298682	19/56 (34%)
calu	NP_998840.1	EFh_CREC_Calumenin	37..299	CDD:320026	91/269 (34%)
		EF-hand motif	37..66	CDD:320026	11/29 (38%)
		EF-hand motif	72..101	CDD:320026	9/28 (32%)
		EF-hand motif	108..137	CDD:320026	7/28 (25%)
		EF-hand motif	155..184	CDD:320026	11/29 (38%)
		EF-hand motif	192..221	CDD:320026	10/28 (36%)
		EF-hand motif	233..262	CDD:320026	11/28 (39%)
		EF-hand motif	269..299	CDD:320026	11/29 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920