DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31650 and Rcn1

DIOPT Version :9

Sequence 1:	NP_001162879.1	Gene:	CG31650 / 326150	FlyBaseID:	FBgn0031673	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001102056.1	Gene:	Rcn1 / 362182	RGDID:	1311292	Length:	325	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	116/338 - (34%)
Similarity:	187/338 - (55%)	Gaps:	37/338 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGE---DGEHNVEFDHEAIIGN 76
            :||:.|:...|.             :.||||      .|.....||   :...:.::||||.:|.
  Rat    15 LALVLALRAKPT-------------VRKERV------VRPDSELGERPPEDNQSFQYDHEAFLGK 60

  Fly    77 TKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEEAADRFEEIDQD 141
             ::::.||.|||||||.||..::..:|.:.|..:...|||.||.|..|:...:..|..:::.|:|
  Rat    61 -EDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKVWIKRVQKRYIYDNVAKVWKDYDRD 124

  Fly   142 ADERITWKEYLQDTYAM---EDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTNKDGVLTLEEF 203
            .||:|:|:||.|.||..   ...:| :::.|:.::   :||:.:|:..|.|:|.:.|...|.|||
  Rat   125 KDEKISWEEYKQATYGYYLGNPAEF-QDSSDHHTF---KKMLPRDERRFKASDLDGDLTATREEF 185

  Fly   204 VLFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGDAASHHDK----EWLITEKERFDKDH 264
            ..|.:|||...|..|::..|::|.|.:.||.::..|::.|..||.|.    :|:::|:|:|:...
  Rat   186 TAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFR 250

  Fly   265 DSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDTFVGSEATDYG 329
            |.|.||.|..||:..||:|.:...|..|..||...:|::.|:.|:..|||:|::.||||:||:||
  Rat   251 DLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYG 315

  Fly   330 DHLQNINHLSDEL 342
            :.|.. ||  |||
  Rat   316 EDLTK-NH--DEL 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31650	NP_001162879.1	EF-hand_7	100..153	CDD:290234	18/52 (35%)
		EFh	100..153	CDD:298682	18/52 (35%)
		EF-hand_7	184..241	CDD:290234	20/56 (36%)
		EFh	184..241	CDD:298682	20/56 (36%)
		EFh	228..281	CDD:298682	19/56 (34%)
Rcn1	NP_001102056.1	EFh_CREC_RCN1	42..308	CDD:320027	92/270 (34%)
		EF-hand motif	42..71	CDD:320027	8/29 (28%)
		EF-hand motif	77..106	CDD:320027	10/28 (36%)
		EF-hand motif	113..142	CDD:320027	12/28 (43%)
		EF-hand motif	164..193	CDD:320027	11/28 (39%)
		EF-hand motif	201..230	CDD:320027	8/28 (29%)
		EF-hand motif	242..271	CDD:320027	13/28 (46%)
		EF-hand motif	278..308	CDD:320027	11/29 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4223
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820