DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31650 and calu-1

DIOPT Version :9

Sequence 1:	NP_001162879.1	Gene:	CG31650 / 326150	FlyBaseID:	FBgn0031673	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001370866.1	Gene:	calu-1 / 180769	WormBaseID:	WBGene00019760	Length:	314	Species:	Caenorhabditis elegans

Alignment Length:	332	Identity:	105/332 - (31%)
Similarity:	171/332 - (51%)	Gaps:	38/332 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LCAVALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGEDGEHNVEFDHEAIIGN 76
            |..|.||||.       |:|:.|      |.:..|||        .|.:..||:.::|||..:|.
Worm     4 LLFVGLLAAT-------ALASHH------SSDPSKDG--------EHFKGKEHDKKYDHEQFLGK 47

  Fly    77 TKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEEAADRFE--EID 139
             ..|.|||.|:|::||.:|..|:..||.:.|.||:.:|||..|....|:....:....::  :.:
Worm    48 -DTAAEFDELTPEKSKEKLAKLVPKMDADSDGFIEENELKDHINFMQKRYVNNDVDRTWKNYKAE 111

  Fly   140 QDADERITWKEYLQDTYAMEDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTNKDGVLTLEEFV 204
            :..|.:|.|::|.:..|...|...::.:.:|      .|||.:|::.:..||.:.:|.|...|:.
Worm   112 KIVDGKIKWEDYREMVYGSADGAGQELSPEY------AKMIARDEKRWAVADYDSNGALDRTEYG 170

  Fly   205 LFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGDAASHHD--------KEWLITEKERFD 261
            .|.:||:...|..:::..|:.|.|.:.||.::..|::||.....|        .:|:.:|:|.|.
Worm   171 CFMHPEDCDHMRDVVVAETVDDIDKNKDGSVDLDEYIGDMYRPDDYPELNGKEPDWVQSEREMFK 235

  Fly   262 KDHDSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDTFVGSEAT 326
            :..|.:|||.|..:|:..||:|.....|..|..||....|::.|.:|:..||:.:|||||||:||
Worm   236 EHRDKDGDGKLNQEEMRDWIMPVGFDHAEAEARHLVGIADDNKDGKLNLDEIVAHYDTFVGSQAT 300

  Fly   327 DYGDHLQ 333
            |||:.||
Worm   301 DYGEQLQ 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31650	NP_001162879.1	EF-hand_7	100..153	CDD:290234	14/54 (26%)
		EFh	100..153	CDD:298682	14/54 (26%)
		EF-hand_7	184..241	CDD:290234	15/56 (27%)
		EFh	184..241	CDD:298682	15/56 (27%)
		EFh	228..281	CDD:298682	17/60 (28%)
calu-1	NP_001370866.1	EFh_CREC_Calumenin_like	29..296	CDD:320024	82/273 (30%)
		EF-hand motif	29..57	CDD:320024	11/28 (39%)
		EF-hand motif	64..93	CDD:320024	11/28 (39%)
		EF-hand motif	100..131	CDD:320024	5/30 (17%)
		EF-hand motif	148..177	CDD:320024	8/28 (29%)
		EF-hand motif	185..214	CDD:320024	8/28 (29%)
		EF-hand motif	230..259	CDD:320024	12/28 (43%)
		EF-hand motif	266..295	CDD:320024	11/28 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920