DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31650 and Calu

DIOPT Version :9

Sequence 1:NP_001162879.1 Gene:CG31650 / 326150 FlyBaseID:FBgn0031673 Length:342 Species:Drosophila melanogaster
Sequence 2:NP_031620.1 Gene:Calu / 12321 MGIID:1097158 Length:315 Species:Mus musculus


Alignment Length:347 Identity:120/347 - (34%)
Similarity:187/347 - (53%) Gaps:51/347 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LLPLTLCAVALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGE--DGEH----N 65
            |:.|:||.              |.|.|...||   |:||          ||..:  |..|    |
Mouse     7 LMCLSLCT--------------AFALSKPTEK---KDRV----------HHEPQLSDKVHNDAQN 44

  Fly    66 VEFDHEAIIGNTKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEE 130
            .::||:|.:| .:||:.||.|:|:|||.||..::..:|.:||.|:...|||.||..:.|:...|:
Mouse    45 FDYDHDAFLG-AEEAKSFDQLTPEESKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHED 108

  Fly   131 AADRFEEIDQDADERITWKEYLQDT--YAMEDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTN 193
            ...:::..|.:.|..::|:||...|  |.::|.|      ..|.:..:|.|:: |:..|..||.:
Mouse   109 VERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPD------PDDGFNYKQMMVR-DERRFKMADKD 166

  Fly   194 KDGVLTLEEFVLFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGDAASH----HDKEWLI 254
            .|.:.|.|||..|.:|||:..|..|:::.||:|.|.:.||.|:.:|::||..||    .:.||:.
Mouse   167 GDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNADEPEWVK 231

  Fly   255 TEKERFDKDHDSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDT 319
            ||:|:|.:..|.|.||.:..:|...||:||:...|..|..||...:|::.|.:|:..||::.||.
Mouse   232 TEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDL 296

  Fly   320 FVGSEATDYGDHLQNINHLSDE 341
            ||||:|||:|:.|  :.|  ||
Mouse   297 FVGSQATDFGEAL--VRH--DE 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31650NP_001162879.1 EF-hand_7 100..153 CDD:290234 16/52 (31%)
EFh 100..153 CDD:298682 16/52 (31%)
EF-hand_7 184..241 CDD:290234 22/56 (39%)
EFh 184..241 CDD:298682 22/56 (39%)
EFh 228..281 CDD:298682 20/56 (36%)
CaluNP_031620.1 EFh_CREC_Calumenin 37..299 CDD:320026 94/269 (35%)
EF-hand motif 37..66 CDD:320026 11/29 (38%)
EF-hand motif 72..101 CDD:320026 11/28 (39%)
EF-hand motif 108..137 CDD:320026 6/28 (21%)
EF-hand motif 155..184 CDD:320026 11/29 (38%)
EF-hand motif 192..221 CDD:320026 11/28 (39%)
EF-hand motif 233..262 CDD:320026 11/28 (39%)
EF-hand motif 269..299 CDD:320026 11/29 (38%)
Prevents secretion from ER 312..315 3/5 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4223
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D372250at33208
OrthoFinder 1 1.000 - - FOG0000638
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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