DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CDC50 and ALIS1

DIOPT Version :9

Sequence 1:	NP_573128.2	Gene:	CDC50 / 32615	FlyBaseID:	FBgn0030752	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_566435.1	Gene:	ALIS1 / 820456	AraportID:	AT3G12740	Length:	350	Species:	Arabidopsis thaliana

Alignment Length:	350	Identity:	144/350 - (41%)
Similarity:	189/350 - (54%)	Gaps:	33/350 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTQQAENEESAAA----------KSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPI 55
            ||:....:..:|||          .||||..|.|.||.|||.:|:||...|:.||.:|.|:|||:
plant     1 MSSSNTPSSSAAAAGSIDSSAARRNSKRPKYSKFTQQELPACKPILTPGWVISTFLIISVIFIPL 65

  Fly    56 GVVLLHLSNTANELIIDY-TKCRRSGGNTTCAEYLEANPGVTCPCEVPFVLPSDFNGVVYMYYGL 119
            ||:.|..|....|::..| :.|...........|::.....:|...:  ::|......:|:||.|
plant    66 GVISLFASQDVVEIVDRYDSACIPLSDRANKVAYIQGTGNKSCTRTL--IVPKRMKQPIYVYYQL 128

  Fly   120 TNYYQNHRRYVKSRDDEQLLGHLSQTPSTDCAPFAYDPDSGKPIAPCGAIANSLFNDTLTLLQGG 184
            .|:|||||||||||.|.||.....:.....|.|  .|...|:||.|||.||.||||||..|.:..
plant   129 ENFYQNHRRYVKSRSDSQLRSVKDENQIDACKP--EDDFGGQPIVPCGLIAWSLFNDTYVLSRNN 191

  Fly   185 SEIKLLKTGIAWPSDKRVKFRNPEGNLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVW 249
            ..:.:.|.||||.|||..||     ..||..:.|.|...  .|.|.|||..|.::   .||||||
plant   192 QGLTVNKKGIAWKSDKEHKF-----GKNVFPKNFQKGNL--TGGASLDPNKPLSD---QEDLIVW 246

  Fly   250 MRTAALPSFRKLYRRLNQTNTNYANGLKSG-NYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNP 313
            |||||||:|||||.::.       :.|:.| |..:.::.||...||.|.|:::|||||.|||||.
plant   247 MRTAALPTFRKLYGKIE-------SDLEKGENIQVTLQNNYNTYSFSGKKKLVLSTTSWLGGKND 304

  Fly   314 FLGIAYIVVGAICITLGLALLFIHM 338
            ||||||:.||.||..|.||...:::
plant   305 FLGIAYLTVGGICFVLALAFTVMYL 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDC50	NP_573128.2	CDC50	67..340	CDD:281387	113/273 (41%)
ALIS1	NP_566435.1	CDC50	71..330	CDD:397450	114/279 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	185	1.000	Domainoid score	I995
eggNOG	1	0.900	-	-		E1_COG5035
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110703
Inparanoid	1	1.050	232	1.000	Inparanoid score	I1130
OMA	1	1.010	-	-		QHG53602
OrthoDB	1	1.010	-	-		D889671at2759
OrthoFinder	1	1.000	-	-		FOG0000577
OrthoInspector	1	1.000	-	-		otm2961
orthoMCL	1	0.900	-	-		OOG6_100927
Panther	1	1.100	-	-	O	PTHR10926
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X371
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840