Protein Alignment CDC50 and TMEM30A

DIOPT Version :9

• Sequence 1: NP_573128.2
• Gene: CDC50 / 32615
• FlyBaseID: FBgn0030752
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_060717.1
• Gene: TMEM30A / 55754
• HGNCID: 16667
• Length: 361
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 193/348 - (55%)
• Similarity: 234/348 - (67%)
• Gaps: 20/348 - (5%)

  Fly    14 AKSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHLSNTANELIIDYTKCRR 78
            ||::||.::||||||||||||:|||.||||.||:||::|||||:.:...||...|:.||||....
Human    23 AKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEP 87

  Fly    79 SGGNTTCAEYLEANPGVT-CPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQLLGHL 142
            |.....|     .:|.|| |.|.:.|.|...|.|.|:|||||:|:|||||||||||||.||.|..
Human    88 SSPCNKC-----LSPDVTPCFCTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDS 147

  Fly   143 SQ--TPSTDCAPFAYDPDSGKPIAPCGAIANSLFNDTLTLLQGGSE-----IKLLKTGIAWPSDK 200
            |.  .||.:|.|:..:.|  ||||||||||||:|||||.|...|::     |.|.|.||||.:||
Human   148 SALLNPSKECEPYRRNED--KPIAPCGAIANSMFNDTLELFLIGNDSYPIPIALKKKGIAWWTDK 210

  Fly   201 RVKFRNPEG--NLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVWMRTAALPSFRKLYR 263
            .||||||.|  ||....:|.:||:.|.|.:..|| .:||||||.|||.||||||||||:||||||
Human   211 NVKFRNPPGGDNLEERFKGTTKPVNWLKPVYMLD-SDPDNNGFINEDFIVWMRTAALPTFRKLYR 274

  Fly   264 RLNQTNTNYANGLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAICIT 328
            .:.:.:..:.. |.:|.|:||:.|||||..|||.|||||||.|.:||||||||||||.||:|...
Human   275 LIERKSDLHPT-LPAGRYSLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFL 338

  Fly   329 LGLALLFI-HMRCSRSNMEMINV 350
            ||:.||.| |...:.||...|.:
Human   339 LGVVLLVINHKYRNSSNTADITI 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDC50	NP_573128.2	CDC50	67..340	CDD:281387	156/283 (55%)
TMEM30A	NP_060717.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		3/5 (60%)
		CDC50	70..349	CDD:397450	157/287 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147988
Domainoid	1	1.000	277	1.000	Domainoid score	I1736
eggNOG	1	0.900	-	-		E1_COG5035
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110703
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2309
Isobase	1	0.950	-	0	Normalized mean entropy	S1172
OMA	1	1.010	-	-		QHG53602
OrthoDB	1	1.010	-	-		D461644at33208
OrthoFinder	1	1.000	-	-		FOG0000577
OrthoInspector	1	1.000	-	-		otm42164
orthoMCL	1	0.900	-	-		OOG6_100927
Panther	1	1.100	-	-	LDO	PTHR10926
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X371
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720