Protein Alignment Cdc50 and TMEM30A

DIOPT Version :10

• Sequence 1: NP_573128.2
• Gene: Cdc50 / 32615
• FlyBaseID: FBgn0030752
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_060717.1
• Gene: TMEM30A / 55754
• HGNCID: 16667
• Length: 361
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 193/348 - (55%)
• Similarity: 234/348 - (67%)
• Gaps: 20/348 - (5%)

  Fly    14 AKSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHLSNTANELIIDYTKCRR 78
            ||::||.::||||||||||||:|||.||||.||:||::|||||:.:...||...|:.||||....
Human    23 AKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEP 87

  Fly    79 SGGNTTCAEYLEANPGVT-CPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQLLGHL 142
            |.....|     .:|.|| |.|.:.|.|...|.|.|:|||||:|:|||||||||||||.||.|..
Human    88 SSPCNKC-----LSPDVTPCFCTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDS 147

  Fly   143 SQ--TPSTDCAPFAYDPDSGKPIAPCGAIANSLFNDTLTLLQGGSE-----IKLLKTGIAWPSDK 200
            |.  .||.:|.|:..:.|  ||||||||||||:|||||.|...|::     |.|.|.||||.:||
Human   148 SALLNPSKECEPYRRNED--KPIAPCGAIANSMFNDTLELFLIGNDSYPIPIALKKKGIAWWTDK 210

  Fly   201 RVKFRNPEG--NLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVWMRTAALPSFRKLYR 263
            .||||||.|  ||....:|.:||:.|.|.:..|| .:||||||.|||.||||||||||:||||||
Human   211 NVKFRNPPGGDNLEERFKGTTKPVNWLKPVYMLD-SDPDNNGFINEDFIVWMRTAALPTFRKLYR 274

  Fly   264 RLNQTNTNYANGLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAICIT 328
            .:.:.:..:.. |.:|.|:||:.|||||..|||.|||||||.|.:||||||||||||.||:|...
Human   275 LIERKSDLHPT-LPAGRYSLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFL 338

  Fly   329 LGLALLFI-HMRCSRSNMEMINV 350
            ||:.||.| |...:.||...|.:
Human   339 LGVVLLVINHKYRNSSNTADITI 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc50	NP_573128.2	CDC50	59..343	CDD:460906	158/294 (54%)
TMEM30A	NP_060717.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		3/5 (60%)
		CDC50	70..353	CDD:460906	158/291 (54%)