DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CDC50 and Tmem30a

DIOPT Version :9

Sequence 1:	NP_573128.2	Gene:	CDC50 / 32615	FlyBaseID:	FBgn0030752	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	XP_006243497.1	Gene:	Tmem30a / 300857	RGDID:	1303315	Length:	364	Species:	Rattus norvegicus

Alignment Length:	351	Identity:	193/351 - (54%)
Similarity:	235/351 - (66%)	Gaps:	21/351 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AAKSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHLSNTANELIIDYTKCR 77
            |||::||.::||||||||||||:|||.|||||||:||::|||||:.:...||...|:.||||...
  Rat    22 AAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTE 86

  Fly    78 RSGGNTTCAEYLEANPGVT-CPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQLLGH 141
            .|.....|     .:|.|| |.|.:.|.|...|.|.|:|||||:|:|||||||||||||.||.|.
  Rat    87 PSSPCNKC-----LSPNVTSCVCIINFTLEQSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGD 146

  Fly   142 LSQ--TPSTDCAPFAYDPDSGKPIAPCGAIANSLFNDTLTLLQGGSE-------IKLLKTGIAWP 197
            .|.  .||.:|.|:..:.|  ||||||||||||:|||||.|....:|       |.|.|.||||.
  Rat   147 PSALLNPSKECEPYRRNED--KPIAPCGAIANSMFNDTLELFLVANESDPKPVPILLKKKGIAWW 209

  Fly   198 SDKRVKFRNPEG--NLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVWMRTAALPSFRK 260
            :||.||||||.|  :|....:..:||:.|.|.:.:|||::..||||.|||.||||||||||:|||
  Rat   210 TDKNVKFRNPPGKDSLQEKFKDTTKPVNWHKPVYELDPDDESNNGFINEDFIVWMRTAALPTFRK 274

  Fly   261 LYRRLNQTNTNYANGLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAI 325
            |||.:.:|:..:.. |.:|.|.|||.|||||..|||.|||||||.|.:||||||||||||.:|:|
  Rat   275 LYRLIERTDDLHPT-LPAGQYYLNITYNYPVHFFDGRKRMILSTISWMGGKNPFLGIAYITIGSI 338

  Fly   326 CITLGLALLFI-HMRCSRSNMEMINV 350
            ...||:.||.| |...:.||...|.:
  Rat   339 SFLLGVVLLVINHKYRNSSNTADITI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDC50	NP_573128.2	CDC50	67..340	CDD:281387	154/285 (54%)
Tmem30a	XP_006243497.1	CDC50	75..353	CDD:281387	154/285 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341857
Domainoid	1	1.000	257	1.000	Domainoid score	I1949
eggNOG	1	0.900	-	-		E1_COG5035
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110703
Inparanoid	1	1.050	317	1.000	Inparanoid score	I2468
OMA	1	1.010	-	-		QHG53602
OrthoDB	1	1.010	-	-		D461644at33208
OrthoFinder	1	1.000	-	-		FOG0000577
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100927
Panther	1	1.100	-	-	LDO	PTHR10926
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X371
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810