DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31642 and AgaP_AGAP002670

DIOPT Version :9

Sequence 1:	NP_723159.1	Gene:	CG31642 / 326149	FlyBaseID:	FBgn0051642	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	XP_312254.5	Gene:	AgaP_AGAP002670 / 3290667	VectorBaseID:	AGAP002670	Length:	575	Species:	Anopheles gambiae

Alignment Length:	577	Identity:	122/577 - (21%)
Similarity:	197/577 - (34%)	Gaps:	175/577 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 CENCKISDFQGRRYTCRFCAEYTLCGKCFDANHLPASPQHRYYHPMSVYYAYAEYQLYFGGEPFC 81
            |::|..|:|:||||.|..|.:|.||..|::..  ..:.:|...|||......::::||:|||...
Mosquito     9 CDSCLKSNFRGRRYKCLICYDYDLCATCYEEG--ATTTRHSTDHPMQCILTQSDFELYYGGEVLQ 71

  Fly    82 GDHKVAQSYKCALCDVRGLSTAHLFMHLLQEHRDHRDHDAYLSLVNTLYIADNGMEQQVPV---- 142
            .|.  .||:.|..|...|||.:.|..|:..||                  .|.|:|...||
Mosquito    72 ADQ--PQSFTCPYCKRMGLSDSALLEHVSAEH------------------TDTGLEVVCPVCAAL 116

  Fly   143 --PQPS----------SQTRSTRSRNLAS----------------------VR--PVAG---GNT 168
              .:|:          |....:.||:|.|                      ||  |.:|   |..
Mosquito   117 PGGEPNFVTDDFARHLSLEHRSGSRDLISFLISFSNMLLNLSSPSAIRHGGVRRMPHSGRALGGP 181

  Fly   169 RSEQRTEQVFDSALSLALMVVQLDNMDSTAADFPERCYEILQQTETVLMQHRSSRVP---DMEAI 230
            || :|:...|.|:..      .|..:..:..:..:...|:|||...|    |....|   .::.:
Mosquito   182 RS-RRSNMHFSSSGG------GLSTLSPSGRESVDPIAELLQQLSNV----RRGGAPQPSQLQQL 235

  Fly   231 ESFVRVIEDQVVTSMA-------DRRQRLGASSSSLHRLTRIEAISPGTNTALAMGMRAAMPVLV 288
            :..:::...||..|.|       .|||:..|..||....|       |.|.. |:|...|.|
Mosquito   236 QMQIQLERQQVTVSAARQQLERLPRRQQQPAVVSSAPNAT-------GVNNN-AIGATQANP--- 289

  Fly   289 DQPTTMVRRQTARRTGEPIGIALQSAVASSSRSGKA---GSSSGVAKAQTKTQGDQPTKKVSTVI 350
              ..|::......|.| ||..:....:.|:...|..   |:..|.|.|.:..|..|
Mosquito   290 --NHTIITLNAGGRDG-PIAASSSLPMVSTGVGGVCNVPGTVGGAAGAGSSAQQSQ--------- 342

  Fly   351 TSPLKDKRFLCSKLV------SGNGQKWESKLLKATFTEAMFCSMLADEELFQPPIGLPWTANFM 409
                    ||.::.:      :...|....:..::.|.:|:..|.:|:.:.|
Mosquito   343 --------FLMARFMVPTMDDAEQTQLGRDRADRSQFVQALMLSTIANVQPF------------- 386

  Fly   410 LDAVEPSGSVKSNGKLLLYPVKTKELMERFYRGLAEYKTWIGYQTEPTAESKATELPSASTSSAY 474
                                  .|...|.....|:.....:|..|...:.:..:.:...::....
Mosquito   387 ----------------------NKNAEEELSDELSSMNLGVGGGTNTCSSTVNSSVKRPASDDGG 429

  Fly   475 FTVLGDIPYADSGSDDLESNASEEMASDLHGEGNSDDLAGLEEDKESGEEENGDEDD 531
            .|.:|::...|.|:.| .||..:|       :||.|..      |...:..||..:|
Mosquito   430 ETAVGELLLQDGGATD-SSNYGKE-------DGNCDSF------KLGADSANGGSND 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31642	NP_723159.1	ZZ_PCMF_like	15..65	CDD:239078	18/47 (38%)
AgaP_AGAP002670	XP_312254.5	ZZ_PCMF_like	7..55	CDD:239078	18/47 (38%)
AgaP_AGAP002670	XP_312254.5	zf-Di19	76..137	CDD:283297	18/78 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004459
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12268
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010