Protein Alignment mRpS18A and Mrps18a

DIOPT Version :10

• Sequence 1: NP_731252.1
• Gene: mRpS18A / 326141
• FlyBaseID: FBgn0051450
• Length: 155
• Species: Drosophila melanogaster
• Sequence 2: NP_081044.1
• Gene: Mrps18a / 68565
• MGIID: 1915815
• Length: 196
• Species: Mus musculus
• Alignment Length: 693
• Identity: 124/693 - (17%)
• Similarity: 229/693 - (33%)
• Gaps: 174/693 - (25%)

  Fly    31 MLRNTKVSNFASTFRKDLASSMTTGFKEENVDKRKKKVEELTMAQNLREASVDLDYFQTSCLHRV 95
            :|..|::|........||....|.......:.:.|:....:.::..|..::.||...|    .|:
Mouse   571 ILDKTRMSILPQKPYSDLGLGQTQDDSIVGLRQNKQTPPTMPVSGTLSSSNPDLAQGQ----QRI 631

  Fly    96 INAYGT-------------VLHA-EVDEKVKLEMAMERRVYEELA--------------PFSEYE 132
            |: |.|             ||.. :.|::.:..:|.......|.|              .||..|
Mouse   632 ID-YSTQPPAPGFTQLQDQVLRIFKADQQSRYLLANRDTTAREAANLAIKEFGLSASPEAFSLCE 695

  Fly   133 KNV--------NKLKDKLNLVSTDLEIAQKDLEKENSMTHQ--ESLDAIQMKYEGMKDALVTDIF 187
            .:|        .:|.|:|:.::..::::.:...|.|..|..  ..::|::|:.|.:...|  .:.
Mouse   696 VSVTQEGVIKQRRLPDQLSKLADRIQLSARYYLKSNMETETLCSDVEALEMQRESVVPLL--SLS 758

  Fly   188 ASSVSKEFQLNEHMLTSMNLKRDYFKKMYEMYEKAIPEVERMIATALPRPVFGVP--------LD 244
            :..::.:.....::|.|.....||...:::::.:..|...|.....:.:..|.|.        |.
Mouse   759 SMEIANQLSARNYLLFSCIEPTDYINDLFKLHPQEPPTNLRNFEGLVNQETFWVATEIVQETNLA 823

  Fly   245 EHLSIQKERISGVLTKCCDFLRQNGMNERGIFRVSG-NASKIKRIRAALD--AGQFDADEKHYNN 306
            :.:.|.|..|. :...|.|....|.|    ...:|| |.:.:.|:|:..:  .|:::
Mouse   824 KRVKIIKHFIK-IALHCRDCKNFNSM----FAIISGFNLAPVSRLRSTWERLPGKYE-------- 875

  Fly   307 DPHAVASTLKAYLRELPDPLTMDSLQSDWVEAINLEGE--ERFSAIDRCLKKMTRGHRQNLIYLM 369
                   .|.|.|:::.||....:...:.:...||:..  ..|..|.:.|..:..|:...:..|:
Mouse   876 -------KLLAELQDVFDPSRNMAKYRNLLNKHNLQPPVIPLFPVIKKDLTFLHEGNNSEVDGLV 933

  Fly   370 KFLCDLEAKREETSMNASNLAIVFAPTMTGMIYDGMNTHGVKLTEFMISNGVRIF--------NF 426
            .|        |:..|.|..:                 .|.|::....:...: :|        :.
Mouse   934 NF--------EKLRMIAREI-----------------RHVVRMASITMDPAL-LFKTRKKKWRSL 972

  Fly   427 GALDKLDTSPPSGF--------TRAQSSISPRSFRPKEKAPPPPSQTPSTSGDLINLHSGDDDDF 483
            |:|.::.:|..|..        .|..|.:|.:.....|.......|...|..:    .|.:|...
Mouse   973 GSLSQVSSSSLSDIGTMGGKRKGRRSSFLSAKKLYEVEMMSRRVRQYLDTHSN----ESNEDTLH 1033

  Fly   484 SDDQSPSPFNGGSLTRSHTEHRPNRPPPPKFQSFRAACADTPKSRPISYNIAVGARPNESHSVS- 547
            ....:..|.|..:|..:....|                              :.|.|....|.|
Mouse  1034 ELSMTCEPANSSTLKHAGERRR------------------------------IDASPAGQRSASP 1068

  Fly   548 QPPKGMTVSMEDIIAEAPV--------APERKRLSILSLTGPPRVVPTPTQPSTSQDVATVTDGG 604
            |...|.....:.|..|.|.        .||..:.|..|:...||..|..|.....|.|  |::..
Mouse  1069 QQTNGNHGRKKSISKELPFEGRDRQRKLPEDSQSSTSSILSSPRNSPQSTPRKGPQLV--VSEVS 1131

  Fly   605 DNRTFVSVSGESSSSSPTTSISIPSNVQP----PPQSAKPKPP 643
            |..:.:     |||||....:...::.||    .|.||:...|
Mouse  1132 DQMSLL-----SSSSSELLMVDDHTHTQPHSLAHPLSARRAEP 1169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRpS18A	NP_731252.1	Ribosomal_S18	74..123	CDD:460054	12/62 (19%)
Mrps18a	NP_081044.1	Ribosomal_S18	83..128	CDD:460054