Protein Alignment CG31445 and TMA108

DIOPT Version :9

• Sequence 1: NP_001263064.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_012129.1
• Gene: TMA108 / 854669
• SGDID: S000001399
• Length: 946
• Species: Saccharomyces cerevisiae
• Alignment Length: 1048
• Identity: 230/1048 - (21%)
• Similarity: 423/1048 - (40%)
• Gaps: 246/1048 - (23%)

  Fly    15 LSVANSISRYNHYRLPTALRPQRYYLRILTLLESPDDLRFAGNVQIVIKALQNTRNIT------- 72
            ||:.|.:.. :||.|...:.|::         .||:   |.|:..|.:|...|:..:.
Yeast     6 LSLENPVVP-SHYELRLEIDPKQ---------SSPN---FKGSAIIHLKFNPNSTTLASIEDSFT 57

  Fly    73 ---LHSKNLTIDESRITLRQISGAGNMDNCVSSTS------VNPTHDYYIFHTCKELLA----GN 124
               ||||:|.:..:..|:    |:...|..:|..:      .|......:.:.|..:|:    |.
Yeast    58 QFKLHSKDLIVLSAHATI----GSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGK 118

  Fly   125 VYKLFLPFSADLT---PQLFGYYRSSYKDPVT-NKTRWLSATQFEPSSARKAFPCFDEPGFKASF 185
            :        .|:.   .:.||.:::::.|..| .....:.||..:|.||...|||.|||..|::|
Yeast   119 I--------RDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTF 175

  Fly   186 VVTLGYHKQFNALSNMPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPS------- 243
            .:.:....|:.|:||.||..:...:|...:: .:|.::..|:|.:..:|:.|..|..:
Yeast   176 QLNIATDAQYKAVSNTPVEMVEALDSSQKHL-VKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGD 239

  Fly   244 -TLPNGALFRTWARPNAIDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWG 307
             |:| .:::..|...||....|...::.|.:    |.:|...|||||:|.:.:|..|..||||:|
Yeast   240 RTIP-VSIYAPWDIANAAFTLDTVQKYLPLL----ESYFKCPYPLPKLDFVLLPYLSDMAMENFG 299

  Fly   308 LVKYRESTLLYSPTHSSLAD---KQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGL 369
            ::..:.:.||..|  ::||:   ::....:|.|||.|||.||.::...|..||.||.|||::|..
Yeast   300 MITIQLNHLLIPP--NALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACH 362

  Fly   370 GVQEIYPEWHSRDKGSLTALMTA--FRLDSL----------VSSHPISRPIQMVTEIE----ESF 418
            .:::         .|.|:...|:  :.|..:          |:...|.:..|..|.|:    :.|
Yeast   363 ILEQ---------NGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIF 418

  Fly   419 DAISYQKGSAVLRMMHLFMGEESFRTGLR---EYLKLYAYKNAEQNNLWESLTTAAHQNGALPGH 480
            |..:|.||..:||.:.|..||...:.||.   |..|.:..::.:..::|..:       |.....
Yeast   419 DPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHI-------GKFLKS 476

  Fly   481 YDINTIMDSWTLQTGFPVLNI---TRDYSTGTAEITQERYLRNSQIPQADRVG--CWWVPLSYTT 540
            .:|...:.|||...|.||:.:   .:|..|.| ::||.|::......:.|::.  .:.|||....
Yeast   477 QNITNFVSSWTRTPGLPVVKVEVEEKDGKTQT-KLTQHRFINQLSTEEKDQLEDVPYQVPLFGVL 540

  Fly   541 QD-ENDFNNTSPKAWMECSSTDEGVPTTIDHSAGPEEWLILNIQLSTPYKANYDAR------NWK 598
            .| :.|..|.        ..||..:  ..|:..     |::|......|:.:|::.      |.|
Yeast   541 PDGKMDTKNV--------LLTDRTL--KFDYPI-----LVINHLAQGYYRVSYESEECYALINDK 590

  Fly   599 LLIDTLNSKDFQSIHVINRAQLIDDVLYFAWTGEQDYETAL------QVTNYLRRERDLI----- 652
            :..:||:..|.:.| .::.:|.|         |::.::.::      ::.|::......|
Yeast   591 ITEETLSEIDLRKI-FLDLSQFI---------GDEGFQNSIHLHGLFKILNHIASPSTKIASKYW 645

  Fly   653 -PWKSALDNLKLLNRILRQTPNFGSFKRYMQKLLTPIYEHLHGMNDTFSLMTQQDEVLLKTTVVN 716
             |....|:.|:.::|....:....||.:  :|::.|::..:...:..|...|...|:.:.:.|:.
Yeast   646 DPLSKGLEVLQTIDRASLTSSKLQSFLK--KKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLF 708

  Fly   717 VACQYDVSDCVTQAQAYFRRWRAETNPDENHPVPLNLRSTV------YCTAISQGTEEDWNFLWS 775
            :  ..:.:.|....|.||:  .....|..:  |||.|.:::      :|..|.|     |..::.
Yeast   709 L--NKNSAKCAELCQIYFK--HLLQGPRSS--VPLELVNSILVVVSQHCANIKQ-----WKKIFD 762

  Fly   776 RYRKSNVASERQTILSTLGCSKEVWILQRYMEKSFHPKSAIRKQDSSLCFQAVASREVGFLLAKQ 840
            ..::|          |..|.:..|  :..|.:.|         .::::..|..|...:||.|...
Yeast   763 LVKRS----------SCTGITNHV--INMYDQNS---------SETAMLIQNGAIESLGFCLDSD 806

  Fly   841 Y------FI------ENVEL------------IHKYYYPQTRVMSRLL------------TPLSE 869
            .      ||      |.:||            ::|...||.:|:...:            ...:.
Yeast   807 IVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATR 871

  Fly   870 QVSTIND-LNK---------FRSFANDS----RHFLKGIRQAMQQSLETMLTNVQWMDWNYHKFS 920
            :.:|..| |:|         |:.|..|.    ..|:...::.:.||| ..|.:: |......:.|
Yeast   872 KGTTTGDHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSL-LSLDDI-WASVQQDEES 934

  Fly   921 R-TIRHHL 927
            | |||..|
Yeast   935 RKTIRRDL 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_001263064.1	Peptidase_M1	28..426	CDD:279741	110/448 (25%)
		M1_APN_2	43..497	CDD:189008	126/507 (25%)
		ERAP1_C	578..904	CDD:288671	71/399 (18%)
TMA108	NP_012129.1	PepN	7..941	CDD:223385	228/1044 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910