DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31445 and AT1G63770

DIOPT Version :9

Sequence 1:	NP_001263064.1	Gene:	CG31445 / 326140	FlyBaseID:	FBgn0051445	Length:	927	Species:	Drosophila melanogaster
Sequence 2:	NP_001117543.4	Gene:	AT1G63770 / 842681	AraportID:	AT1G63770	Length:	987	Species:	Arabidopsis thaliana

Alignment Length:	937	Identity:	192/937 - (20%)
Similarity:	312/937 - (33%)	Gaps:	268/937 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PQRYYLRILTLLESPD------DLRFA-GNVQIVIKA-LQNTRNITLHSKNLTIDESRITLRQIS 91
            |:..:|:..|   .||      ||.|: |..:.::.: ::.:..:...|..|.:|...:.|..:.
plant    96 PKEIFLKNYT---KPDYYFETVDLSFSLGEEKTIVSSKIKVSPRVKGSSAALVLDGHDLKLLSVK 157

  Fly    92 GAGNM----DNCVSSTSVN----PTHDYYIFHTCKELLAGNVYKLFLPFSADLTP----QLFGYY 144
            ..|.:    |..:.|..:.    |..:.::                |....::.|    .|.|.|
plant   158 VEGKLLKEGDYQLDSRHLTLPSLPAEESFV----------------LEIDTEIYPHKNTSLEGLY 206

  Fly   145 RSSYKDPVTNKTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQF--------NALSNM 201
            :||..          ..||.|....||.....|.|...|.:...:...|..        |.:|..
plant   207 KSSGN----------FCTQCEAEGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNGNLISQG 261

  Fly   202 PVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPSTLPNGA----LFRTWARPNAIDQ 262
            .:...| |.:|    |   ::......||.|........:..|....:    ..:.|.....:.:
plant   262 DIEGGR-HYAL----W---EDPFKKPCYLFALVAGQLVSRDDTFTTRSGRQVSLKIWTPAEDLPK 318

  Fly   263 CDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYSPTHSSLAD 327
            ..:|.......:::.|:.||:.|.|...:.:|||||:.|||||..|..:....:|.||..::.||
plant   319 TAHAMYSLKAAMKWDEDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASPETATDAD 383

  Fly   328 KQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRDKGSLTALMTA 392
            ...:..||.||..|.|.||.||.:.|..|.|.||...:    ..||.     |.|.||.|....|
plant   384 YAAILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVF----RDQEF-----SSDMGSRTVKRIA 439

  Fly   393 ---------FRLDSLVSSHPISRPIQMVTEIEESFDAISYQK------------GSAVLRMMHLF 436
                     |..|:...:||: ||...: :::..:....|:|            |:.|:||....
plant   440 DVSKLRIYQFPQDAGPMAHPV-RPHSYI-KMDNFYTVTVYEKVWLFTNSVLLYAGAEVVRMYKTL 502

  Fly   437 MGEESFRTGLREYLKLYAYKNAEQNNLWESLTTAAHQ-NGALPGHYDINTIMDSWTLQTGFPVLN 500
            :|.:.||.|    :.||..::.||....|....|... |.|     |....: .|..|.|.||:.
plant   503 LGTQGFRKG----IDLYFERHDEQAVTCEDFFAAMRDANNA-----DFANFL-QWYSQAGTPVVK 557

  Fly   501 ITRDYS----TGTAEITQERYLRNSQIPQADRVGCWWVPLSYTTQDENDFNNTSPKAWMECS-ST 560
            :...|:    |.:.:.:||......| |..:..   ::|:.....|.:..:.|......:.: .|
plant   558 VVSSYNADARTFSLKFSQEIPPTPGQ-PTKEPT---FIPVVVGLLDSSGKDITLSSVHHDGTVQT 618

  Fly   561 DEGVPTTIDHSAGPEEWLILNIQ----------LSTPYKANYDARNWKLLIDTLNSKDFQSIHVI 615
            ..|..|.:..:...||::..:|.          .|.|.:...|..|
plant   619 ISGSSTILRVTKKEEEFVFSDIPERPVPSLFRGFSAPVRVETDLSN------------------- 664

  Fly   616 NRAQLIDDVLYFAWTGEQDYETALQVTNYLRRERDLIPWKSALDNLKLL---------NRILRQT 671
                   |.|:|....:.|.....:....|.|              ||:         |:.|...
plant   665 -------DDLFFLLAHDSDEFNRWEAGQVLAR--------------KLMLNLVSDFQQNKPLALN 708

  Fly   672 PNF----GSF-------KRYMQKLLTPIYEHLHGMNDTFSLMTQQDEVLLKTTVVNVACQYDVSD 725
            |.|    ||.       |.::.|.:|     |.|..:...:|...|                 .|
plant   709 PKFVQGLGSVLSDSSLDKEFIAKAIT-----LPGEGEIMDMMAVAD-----------------PD 751

  Fly   726 CVTQAQAYFRRWRAETNPDENHPVPLNLRST-VYCTAISQGTEEDWNFLWSRYRKSNVASE--RQ 787
            .|...:.:.|:..|....:|...:..|.||| .|.                 :..||:|..  :.
plant   752 AVHAVRKFVRKQLASELKEELLKIVENNRSTEAYV-----------------FDHSNMARRALKN 799

  Fly   788 TILSTLGCSKEVWILQRYMEKSFHP-KSAIRKQDSSLCFQAVA--SREVG--------------- 834
            |.|:.|...::    ..|||.:.:. |.|....|.   |.|:|  |:..|
plant   800 TALAYLASLED----PAYMELALNEYKMATNLTDQ---FAALAALSQNPGKTRDDILADFYNKWQ 857

  Fly   835 --FLLAKQYFI--------ENVELIHK 851
              :|:..::|:        .|||.:.|
plant   858 DDYLVVNKWFLLQSTSDIPGNVENVKK 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_001263064.1	Peptidase_M1	28..426	CDD:279741	97/443 (22%)
		M1_APN_2	43..497	CDD:189008	115/507 (23%)
		ERAP1_C	578..904	CDD:288671	59/335 (18%)
AT1G63770	NP_001117543.4	pepN	92..987	CDD:237585	192/937 (20%)
AT1G63770	NP_001117543.4	M1_APN_1	103..985	CDD:189007	190/930 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820