Sequence 1: | NP_001263064.1 | Gene: | CG31445 / 326140 | FlyBaseID: | FBgn0051445 | Length: | 927 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000886.1 | Gene: | LTA4H / 4048 | HGNCID: | 6710 | Length: | 611 | Species: | Homo sapiens |
Alignment Length: | 616 | Identity: | 139/616 - (22%) |
---|---|---|---|
Similarity: | 245/616 - (39%) | Gaps: | 137/616 - (22%) |
- Green bases have known domain annotations that are detailed below.
Fly 20 SISRYNHYRLPTALRPQRYYLRILTLLESPDDLRFAGNVQIVIKALQ-NTRNITLHSKNLTIDES 83
Fly 84 RITLRQISGA-GNMDNCVSSTSVNPTHDYYIFHTCKELLAGNVYKLFLPFSADLTPQLFGYYRSS 147
Fly 148 YK-DPVTNKTRWLSATQ---------FEPSSA---RKAFPCFDEPGFKASFVVTLGYHKQFNALS 199
Fly 200 NMPVR--EIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFK---PSTLPNGALFRTWARPNA 259
Fly 260 IDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAV-PDFSAGAMENWGLVKYRESTLLYSPTHS 323
Fly 324 SLADKQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPE--WHSRDKGSL 386
Fly 387 TALMTAFRLDSLVSSHPISRPIQMVTEIEE--SFDAISYQKGSAVL-RMMHLFMGEESFRTGLRE 448
Fly 449 YLKLYAYKNAEQNNLWESLTTAAHQNGALPGHYDINTIMD--SWTLQTGFPVLNITRDYSTGTAE 511
Fly 512 ITQERYLRNSQIPQADRVGCWWVPLSYTTQDENDFNNTSPKAWMECSS---------TDEGVPTT 567
Fly 568 IDHSAGPEE---------------WLILNIQ 583 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG31445 | NP_001263064.1 | Peptidase_M1 | 28..426 | CDD:279741 | 97/422 (23%) |
M1_APN_2 | 43..497 | CDD:189008 | 111/481 (23%) | ||
ERAP1_C | 578..904 | CDD:288671 | 4/6 (67%) | ||
LTA4H | NP_000886.1 | leuko_A4_hydro | 6..608 | CDD:274120 | 139/616 (23%) |
Substrate binding. /evidence=ECO:0000269|PubMed:18804029 | 135..137 | 0/1 (0%) | |||
Substrate binding. /evidence=ECO:0000269|PubMed:18804029 | 267..272 | 1/4 (25%) | |||
Inhibitor ARM1 binding. /evidence=ECO:0000269|PubMed:24591641 | 362..365 | 1/2 (50%) | |||
Substrate binding. /evidence=ECO:0000269|PubMed:18804029 | 564..566 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0308 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |