DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31445 and VB0395L.1

DIOPT Version :9

Sequence 1:	NP_001263064.1	Gene:	CG31445 / 326140	FlyBaseID:	FBgn0051445	Length:	927	Species:	Drosophila melanogaster
Sequence 2:	NP_001024932.1	Gene:	VB0395L.1 / 3564909	WormBaseID:	WBGene00044150	Length:	340	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	72/337 - (21%)
Similarity:	131/337 - (38%)	Gaps:	64/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FLLFVLAIGLDLSVANSISRYNHYRLPTALRPQRYYLRILTLLESPDDL--RFAGNVQIVIKALQ 66
            |::|...:...:..:|::..    .:|....|..|.: .|....:|:.:  .:.|::|:...|..
Worm    33 FVVFGSLLNKTVLPSNNVPS----TIPYITVPSEYNV-FLQFNSTPEAVVREYTGSLQMDFVARD 92

  Fly    67 NTRNITLHSKNLTIDESRITLRQISG------AGNMDNCVSSTSVNPTHDYYIFHTCKELLAGNV 125
            .|:.:..|..: .:..:.|:|...:|      ||..|   .||.|..    ||  ....|.:...
Worm    93 ITQQLFFHRSD-KVKINSISLEDANGTMTAPTAGAYD---KSTGVQA----YI--PLANLTSQES 147

  Fly   126 YKLFLPFSADL-----TPQLFGY--------YRSSYKDPVTNKTRWLSATQFEPSSARKAFPCFD 177
            |.|.:.|..:|     :|:...|        |...:.:.||:.           |..|...||.|
Worm   148 YVLRIDFQGELDSETGSPRNLQYSLPNGTIRYSIVFGNSVTSS-----------SGLRYLMPCLD 201

  Fly   178 EPGFKASFVVTLGYHKQFNALSNMPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKP 242
            .|.|.|.|...:.:..::..:||. ..:|:  :|:. |....|..|..:.:..|..::.|....|
Worm   202 SPDFPAVFNFNIRHSPRYRVISNF-AGQIQ--QSIL-YTATLFAGSFQLDSSQVVLALIDTELAP 262

  Fly   243 STL-PNGALFRTWARPNAIDQCDYAAEFGPKVLQYYEEFFGIR-YPLPKIDQMAVPDFSAGAMEN 305
            .|: .||.....:.|.:.:|...     ..:::|    |...| ..:.|||.:|:||.:  |.:.
Worm   263 VTVQQNGLTINKYYRQSIVDNIS-----TDRIIQ----FMATRSQQIGKIDVLALPDLT--ATQQ 316

  Fly   306 WGLVKYRESTLL 317
            .|:..|.|:.:|
Worm   317 PGITFYNENDVL 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_001263064.1	Peptidase_M1	28..426	CDD:279741	69/313 (22%)
		M1_APN_2	43..497	CDD:189008	66/298 (22%)
		ERAP1_C	578..904	CDD:288671
VB0395L.1	NP_001024932.1	GluZincin	63..>224	CDD:301352	38/182 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900