Protein Alignment CG31445 and Npepps

DIOPT Version :10

• Sequence 1: NP_651689.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_032968.2
• Gene: Npepps / 19155
• MGIID: 1101358
• Length: 920
• Species: Mus musculus
• Alignment Length: 909
• Identity: 267/909 - (29%)
• Similarity: 441/909 - (48%)
• Gaps: 87/909 - (9%)

  Fly    28 RLPTALRPQRYYLRILTLLESPD--DLRFAGNVQIVIKALQNTRNITLHSKNLTIDESRITLRQI 90
            |||..:.|..|     :|...||  |..|.|.::...:..|.|..|.::..::.|    ||   .
Mouse    54 RLPAEVSPINY-----SLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDI----IT---A 106

  Fly    91 SGAGNMDNCVSSTSVN-PTHDYYIFHTCKELLAGNVYKLFLPFSADLTPQLFGYYRSSYKDPVTN 154
            |.|...|..:.:|..| ...|..:..:....|......|.:.|..:|..::.|:|||.|..| ..
Mouse   107 SYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSRYTTP-AG 170

  Fly   155 KTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREIRPHESLANYIWCE 219
            :.|:.:.||||.:.||:||||:|||..||:|.::|...|...|||||.|.:.:|:....|.:..:
Mouse   171 EVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVK 235

  Fly   220 FQESVPMSTYLVAYSVNDFSFKPSTLPNGALFRTWARPNAIDQCDYAAEFGPKVLQYYEEFFGIR 284
            |..:..|||||||:.|.::.|..:...:|...|.:......:|..:|.|...|.|.:|:::|.:.
Mouse   236 FARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVP 300

  Fly   285 YPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYSPTHSSLADKQDLANVIAHELAHQWFGNLVT 349
            |||||||.:|:.||:||||||||||.|||:.||..|.:|..:.:|.:|.|:.|||||||||||||
Mouse   301 YPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVT 365

  Fly   350 MKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRDKGSLTALMTAFRLDSLVSSHPISRPIQMVTEI 414
            |:|||.||||||||:::..|.|...:||:....:........|..||:|.:||||...:...:|:
Mouse   366 MEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEV 430

  Fly   415 EESFDAISYQKGSAVLRMMHLFMGEESFRTGLREYLKLYAYKNAEQNNLWESLTTAAHQNGALPG 479
            :|.||||||.||::|:||:|.::|::.|:.|:..||..:..|||...:|||||.:|:.:
Mouse   431 DEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGK------ 489

  Fly   480 HYDINTIMDSWTLQTGFPVLNITRDYSTGTAEITQERYLRNSQ-------------IPQADRVGC 531
              .|..:|::||.|.|||::.:..:      ::..:|.|:.||             .||
Mouse   490 --PIAAVMNTWTKQMGFPLIYVEAE------QVEDDRVLKLSQKKFCASGPYGGEDCPQ------ 540

  Fly   532 WWVPLSYTTQDENDFNNTSPKAWMECSSTDEGVPTTIDHSAGPEEWLILNIQLSTPYKANYDARN 596
            |.||::.:|.:  |.|....|..|     |:...:.:..:..|::|:.||:.....|:..|.:..
Mouse   541 WMVPITISTSE--DPNQAKLKILM-----DKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAM 598

  Fly   597 WKLLIDTLNSKDFQSIHVINRAQLIDDVLYFAWTGEQDYETALQVTNYLRRERDLIPWKSALDNL 661
            .:.|:..:  :|. |:..::|..|.:|:...|..|.......|:|......|.:...|.....||
Mouse   599 LESLLPGI--RDL-SLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNL 660

  Fly   662 KLLNRILRQTPNFGSFKRYMQKLLTPIYEHL-------HGMNDTFSLMTQQDEVLLKTTVVNVAC 719
            .:|:.:|..|..:...:.:::.:.:||.|.|       .|..|          .||:..|:....
Mouse   661 GILSTLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLD----------ALLRGLVLGKLG 715

  Fly   720 QYDVSDCVTQAQAYFRRWRAETNPDENHPVPLNLRSTVYCTAISQGTEEDWNFLWSRYRKSNVAS 784
            :......:.:|:..|:.     :.:....:..:|||.||.|.:..|.....:.:...::::::..
Mouse   716 KAGHKATLEEARRRFKE-----HVEGKQILSADLRSPVYLTVLKHGDGATLDIMLKLHKQADMQE 775

  Fly   785 ERQTILSTLGCSKEVWILQRYMEKSFHPKSAIRKQDSSLCFQAVA-SREVGFLLAKQYFIENVEL 848
            |:..|...||.:....::|:.:  :|.....:|.||:......|| ..:.|...|.::..:|.|.
Mouse   776 EKNRIERVLGATLSPELIQKVL--TFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEE 838

  Fly   849 IHKYYYPQTRVMSRLLTPLSEQVSTINDLNKFRSFANDSRHFLKGIRQAMQQSLETMLTNVQWM 912
            :|..|.... ::|||:....|..:......:.::|...  |......:.:||..|.:|.|..|:
Mouse   839 LHNRYQGGF-LISRLIKLSVEGFAVDKMAGEVKAFFES--HPAPSAERTIQQCCENILLNAAWL 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_651689.1	M1_APN-Q_like	37..492	CDD:341064	173/457 (38%)
		ERAP1_C	577..905	CDD:463368	66/335 (20%)
Npepps	NP_032968.2	M1_APN-Q_like	62..500	CDD:341064	173/458 (38%)
		ERAP1_C	579..892	CDD:463368	66/335 (20%)
		Nuclear localization signal. /evidence=ECO:0000255	727..731		0/3 (0%)