Protein Alignment CG31445 and Y42A5A.1

DIOPT Version :9

• Sequence 1: NP_001263064.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_505820.1
• Gene: Y42A5A.1 / 179536
• WormBaseID: WBGene00012776
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 976
• Identity: 255/976 - (26%)
• Similarity: 424/976 - (43%)
• Gaps: 192/976 - (19%)

  Fly    21 ISRYNH-YRLPTALRPQRYYLRIL-------TLLESPDDLRFAGNVQIVIKALQNTRNITLHS-- 75
            |:..|| .::|....|..|.:.:.       |:....|:....|:|::...:...:| |.|||
 Worm   144 INNTNHRLQIPQIHIPLLYEVELKLFVPWRPTISFGSDNFSVKGHVRVHFTSGGGSR-ILLHSDS 207

  Fly    76 --------------KNLTIDESRITLRQISGAGNMDNCVSSTSVNPTHDYYIFHTCKELLAGNVY 126
                          :|:|:   ::..||.|...:::                ..|  :::.|..|
 Worm   208 KQHIGDCVVRDELNRNITV---KLVGRQYSQILDLN----------------LET--DMIHGMNY 251

  Fly   127 KLFLPFSADLTPQL-FGYYRSSYKDPVTNKTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLG 190
            .|.:.|.:.:...| :|.:.:.|  ...|:||::.|||.:.|.||..|||.|.|..||.|...:.
 Worm   252 TLDVAFKSAINLNLAYGLFAAPY--TFENETRYVVATQLQISEARTVFPCIDVPDMKAQFDTVII 314

  Fly   191 YHKQFNALSNMPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPSTLPNGALFRTWA 255
            :.....:::||.....:..   ..:....|..:.||||||.|:||:|:.:..:....|...|.:.
 Worm   315 HPTGTTSIANMMENSTKVD---GEWTTTTFHRTPPMSTYLFAFSVSDYPYLETFSGRGVRSRVYC 376

  Fly   256 RP-NAIDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYS 319
            .| ..:|........|| ||.:||::|||.|||.|:|.:.||..|..|||||||:..|::..||:
 Worm   377 DPTKLVDAQLITKSIGP-VLDFYEDYFGIPYPLEKLDVVIVPALSVTAMENWGLITIRQTNGLYT 440

  Fly   320 PTHSSLADKQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEI-YPEWHSRDK 383
            ....:::.|.|:..::||||||||||||||||||.||||||||||.::...|..: ...|...|
 Worm   441 EGRFAISQKHDVQEIVAHELAHQWFGNLVTMKWWNDLWLNEGFATLISVRAVDFLENTTWRYED- 504

  Fly   384 GSLTALMTAFRLDSLVSSHPISRPIQMVTEIEESFD--------AISYQKGSAVLRMMHLFMGEE 440
            .|..:...|.|.|.:.|..|:|      .:...:||        ||.|:|.:.::||:...:.|:
 Worm   505 SSAESQCVALRADQIDSISPVS------GKKNSNFDSYMEIQGKAIIYKKSAIIIRMIERLVEED 563

  Fly   441 SFRTGLREYLKLYAYKNAEQNNLWESLTTAAHQNGALPGH-----YDINTIMDSWTLQTGFPVLN 500
            .||.||:.:|..:.||||:..:|:..| ...|.:.| .||     :.::.:||:|..|..|||::
 Worm   564 IFRQGLKRFLNTFLYKNADHEDLFNVL-VYVHDSSA-GGHLRGQNFSLSDVMDTWIRQAHFPVIH 626

  Fly   501 ITRDYSTGTAEITQERYLRNSQIPQAD-RVGCWWVPLSYTTQDEND-----FNNTSPKAWMECSS 559
            :.|...: ...:.||:|   ..:|:.: ....|.:|:.|.......     ..:|.||.:
 Worm   627 VNRKEGS-LVTLRQEKY---EHVPRDEPEKQVWKIPIFYDDPVSGKHKVFWLTDTQPKVF----- 682

  Fly   560 TDEGVPTTIDHSAGPEEWLILNIQLSTPYKANYDARNWK----LLIDTLNSKDFQSIHVINRAQL 620
             |.|....:|    |.:...:.::        ||...:.    .|:|     ||..|...:|::|
 Worm   683 -DMGGLLVVD----PHQLTYMRLR--------YDMEMYSDITMALMD-----DFTMIPTNSRSRL 729

  Fly   621 IDDVLYFAWTGEQDYETALQVTNYLRRERDLIPWK--SALDNLKLLNRILRQTPNFGSFKRYMQK 683
            |||.|..|..|:..|:....:|.|:.||....|::  ||..:..|....:.:  .:..:|:|::.
 Worm   730 IDDTLAMAENGQLTYKVPFNLTMYMSREIAYRPFQTFSAYLDFFLPRMYIHE--GWSIYKKYLEL 792

  Fly   684 LLTPIYE--HLHGMNDTFSLMTQQDEVLLKTTVVNVACQYDVSDCVTQAQAYFRRWRAETNPD-- 744
            ::...::  :..|::.:|...|  |....:..||..||..:...||..|:..|...|...:.:
 Worm   793 VVGIPFDKFNAEGLDVSFDHNT--DLFHTRQIVVFRACGIEYEPCVRMAKQRFAELRVNCSGENQ 855

  Fly   745 -----ENHPVPLNLRSTVYCTAISQGTEEDWNFLWSRYRKSNVASERQTILSTLG---------- 794
                 |.:.:|..||..||..||:.||:||::||:.::...:...|...|.:.|.
 Worm   856 LLSGMECNKIPYYLRPHVYSAAINDGTQEDFDFLYKKWMIEHYMMEHDNIFTGLCTTNIRENSDR 920

  Fly   795 --------------------CSKEV----WILQRYMEKSFHPKSAIRKQDSSL-CFQAVASREVG 834
                                |||::    :||....|...:.|..:.|...|| ..|.:..|::.
 Worm   921 AWRQVIKNGARENVMVRAQLCSKKLSKNNFILDLLYEDKVYLKEFVDKDRKSLFALQQLLYRKIN 985

  Fly   835 F----LLAKQYFIENVELIHKYYYPQTRVMSRLLTPLSEQV---------------STINDLNKF 880
            :    |.|.:.|..         |||.|.:.:|....|:::               ..|.::.||
 Worm   986 YEEEVLKADEVFKP---------YPQLRWIPKLRAIASDRLDWRKTVAAQFTGNASEAIEEMRKF 1041

  Fly   881 R 881
            :
 Worm  1042 Q 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_001263064.1	Peptidase_M1	28..426	CDD:279741	131/431 (30%)
		M1_APN_2	43..497	CDD:189008	151/492 (31%)
		ERAP1_C	578..904	CDD:288671	80/373 (21%)
Y42A5A.1	NP_505820.1	Peptidase_M1	159..549	CDD:279741	130/424 (31%)
		M1_APN_2	181..623	CDD:189008	150/478 (31%)
		ERAP1_C	688..998	CDD:288671	72/330 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920