Protein Alignment CG31445 and Enpep

DIOPT Version :10

• Sequence 1: NP_651689.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_031960.1
• Gene: Enpep / 13809
• MGIID: 106645
• Length: 945
• Species: Mus musculus
• Alignment Length: 909
• Identity: 281/909 - (30%)
• Similarity: 478/909 - (52%)
• Gaps: 72/909 - (7%)

  Fly    24 YNHYRLPTALRPQRYYLRILTLLESPDDLRFAGNVQIVIKALQNTRNITLHSKNLTIDESRIT-- 86
            :.::|||..:.|..|.|.:..|:|..   |:.|.|.|.:...:.||::.||     |.|::||
Mouse    80 WKNFRLPDFINPVHYDLEVKALMEED---RYTGIVTISVNLSKPTRDLWLH-----IRETKITKL 136

  Fly    87 --LRQISGAG-NMDNCVSSTSVNPTHDYYIFHTCKELLA---GNVYKLFLPFSADLTPQLFGYYR 145
              ||:.||.. .:..|.....    .:|.:....::|.|   .:||:|.:.|...|...|.|:|:
Mouse   137 PELRRPSGEQVPIRRCFEYKK----QEYVVIQAAEDLAATSGDSVYRLTMEFKGWLNGSLVGFYK 197

  Fly   146 SSYKDPVTNKTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREIRPHE 210
            ::|.:  ..:.|.::||..||:.|||:|||||||..|:::.:::.:.|:::||||||..:....:
Mouse   198 TTYME--DGQIRSIAATDHEPTDARKSFPCFDEPNKKSTYSISIIHPKEYSALSNMPEEKSEMVD 260

  Fly   211 SLANYIWCEFQESVPMSTYLVAYSVNDFSFKPSTLPNGALFRTWARPNAIDQCDYAAEFGPKVLQ 275
            .  |:....|.:|||||||||.::|:.|:.......:|...:.:.:||..:..:|||.....|..
Mouse   261 D--NWKKTTFVKSVPMSTYLVCFAVHRFTAIERKSRSGKPLKVYVQPNQKETAEYAANITQAVFD 323

  Fly   276 YYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYSPTHSSLADKQDLANVIAHELA 340
            |:|::|.:.|.|||:|::|:|||..|||||||||.|||:.|||.|..|:.:::|.:|:|:||||.
Mouse   324 YFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDPLLSASSNQQRVASVVAHELV 388

  Fly   341 HQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRDKGSLTALMTAFRLDSLVSSHPIS 405
            ||||||.|||.||.|||||||||::...|||.....:|....:..|..:......|||:||||:.
Mouse   389 HQWFGNTVTMDWWDDLWLNEGFASFFEFLGVNHAEKDWQMLSQVLLEDVFPVQEDDSLMSSHPVV 453

  Fly   406 RPIQMVTEIEESFDAISYQKGSAVLRMMHLFMGEESFRTGLREYLKLYAYKNAEQNNLWESLTTA 470
            ..:....||...||.|||.||:::|||:..::..|.|:.|.:.|||.:.:.||:.::.|:||..|
Mouse   454 VTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLKKFQFANAKTSDFWDSLQEA 518

  Fly   471 AHQNGALPGHYDINTIMDSWTLQTGFPVLNITRDYSTGTAEITQERYLRNSQI----PQADRVGC 531
            ::    ||    :..:||:||.|.|:||:.:     :|...|||:|:|.:|:.    |.::....
Mouse   519 SN----LP----VKEVMDTWTSQMGYPVVTV-----SGRQNITQKRFLLDSKADPSQPPSELGYT 570

  Fly   532 WWVPLSYTTQDEND---FNNTSPKAWMECSSTDEGVPTTIDHSAGPEEWLILNIQLSTPYKANYD 593
            |.:|:.:...|.:.   :|.           .|:| ..|::.:...:.:|.:|......|:.||:
Mouse   571 WNIPVRWADNDNSRITVYNR-----------LDKG-GITLNANLSGDAFLKINPDHIGFYRVNYE 623

  Fly   594 ARNWKLLIDTLNSKDFQSIHVINRAQLIDDVLYFAWTGEQDYETALQVTNYLRRERDLIPWKSAL 658
            ...|..:.:.|:| :.......:|:..|||....|.....:|:.||.:|.||:.|.|.:||:..:
Mouse   624 GGTWDWIAEALSS-NHTRFSAADRSSFIDDAFALARAQLLNYKIALNLTMYLKSEEDFLPWERVI 687

  Fly   659 DNLKLLNRILRQTPN-FGSFKRYMQKLLTPIYEHLHGMNDTFSLMTQQDEVLLKTTVVNVACQYD 722
            .::..:..:...... :...:.|.|..:.|:.: |.|..||.|.:|:    ||:.:::..||:..
Mouse   688 SSVSYIISMFEDDRELYPMIETYFQGQVKPVAD-LLGWQDTGSHITK----LLRASILGFACKMG 747

  Fly   723 VSDCVTQAQAYFRRWRAETNPDENHPVPLNLRSTVYCTAI-SQGTEEDWNFLWSRYRKSNVASER 786
            ..:.:..|...|..|.     ..:..:|:|||..||...: :.|.|..||:...:|:|:::|.|:
Mouse   748 DREALGNASQLFDSWL-----KGSASIPVNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEK 807

  Fly   787 QTILSTLGCSKEVWILQRYMEKSFHPKSAIRKQDSSLCFQAVASREVGFLLAKQYFIENVELIHK 851
            :.:|..|...|:|.:|.||:|....| :.|:.||.....:.::....|..:|..:...|.:.:..
Mouse   808 EKLLYGLASVKDVKLLARYLEMLKDP-NIIKTQDVFTVIRYISYNSYGKTMAWNWIQLNWDYLVS 871

  Fly   852 YYYPQTRVMSRLLTPLSEQVSTINDLNKFRSFANDSRHFLKGIRQAMQQSLETMLTNVQWMDWN 915
            .:....|.:.|::| ::|..:|...|.:.:||.....:...|.: ..:|.|||:..|::|::.|
Mouse   872 RFTINDRYLGRIVT-IAEPFNTELQLWQMQSFFAKYPNAGAGAK-PREQVLETVKNNIEWLNVN 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_651689.1	M1_APN-Q_like	37..492	CDD:341064	173/462 (37%)
		ERAP1_C	577..905	CDD:463368	80/329 (24%)
Enpep	NP_031960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..77
		M1_APN-Q_like	92..531	CDD:341064	172/462 (37%)
		ERAP1_C	607..925	CDD:463368	81/331 (24%)